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Fish oil reverses the altered glucose transporter, phosphorylation, insulin receptor substrate-1 (IRS-1) protein level and lipid contents in skeletal muscle of sucrose-rich diet fed rats
(Elsevier, 2013-01)
The role and underlying mechanisms by which n−3 polyunsaturated fatty acids (PUFA) prevent/reverse SRD-induced insulin resistance (IR) in the muscle are not completely understood. Therefore, we examined: triglyceride, ...
Anti-inflammatory and redox-protective activities of citronellal
(Sociedad de Biología de Chile, 2013)
Dietary Salba (Salvia hispanica L) improves the altered metabolic fate of glucose and reduces increased collagen deposition in the heart of insulin-resistant rats
(Elsevier, 2017-06)
This study reports the effects of dietary Salba (chia) seeds on the mechanisms underlying impaired glucose metabolism in the heart of dyslipemic insulin-resistant rats fed a sucrose-rich diet (SRD). Wistar rats were fed a ...
The unusual lipid binding proteins of parasitic helminths and their potential roles in parasitism and as therapeutic targets
(Elsevier, 2014-10)
In this review paper we aim at presenting the current knowledge on structural aspects of soluble lipid binding proteins (LBPs) found in parasitic helminths and to discuss their potential role as novel drug targets. Helminth ...
Intervening in the β-barrel structure of lipid binding proteins: Consequences on folding, ligand-binding and aggregation propensity
(Elsevier, 2015-02)
Natural β-folds manage to fold up successfully. By contrast, attempts to dissect fragments or peptides from well folded β-sheet proteins have met with insurmountable difficulties. Here we briefly review selected successful ...
Dietary Salba (Salvia hispanica L) seed rich in α-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats
(Elsevier, 2013-09)
This work reports the effect of dietary Salba (chia) seed rich in n-3 -linolenic acid on the morphological and metabolic aspects involved in adipose tissue dysfunction and the mechanism/s underlying the impaired glucose ...
Dietary fish oilnormalized glucose-stimulated insulin secretion in isolated pancreatic islets of dyslipemic rats through mechanisms involving glucose phosphorylation ,peroxisome proliferator-activated receptor γ and uncoupling protein2
(Elsevier, 2013-05)
This study evaluates some possible mechanisms behind the beneficial effects of dietary fish oil (FO) on β cell dysfunction in rats fed a sucrose-rich diet (SRD). Rats were fed a SRD for 6 months. Thereafter, half the rats ...