Search
Now showing items 31-40 of 125
Doença de Alzheimer e sua relação com o alelo ε4 do gene da apolipoproteína E
(Universidade Federal de UberlândiaBrasilCiências Biológicas, 2022)
Role of Ca2+ signaling in mitochondrial dysfunction as a basis of neurodegeneration in early-onset familial Alzheimer’s disease
(Universidad de Chile, 2021)
Familial Alzheimer’s disease (FAD) is characterized by autosomal-dominant
heritability and early onset. Mutations in the gene encoding presenilin-1 (PS1) are
found in approximately 80% of cases of FAD. The etiology of ...
Descripción genotípica y fenotípica de la enfermedad de Alzheimer tardía y familiar precoz : revisiónGenotypic and phenotypic description of late-onset Alzheimer’s disease and early onset familial Alzheimer’s : Review
(Universidad Pontificia Bolivariana, Facultad de MedicinaGrupo de Neurociencias de AntioquiaMedellín, Colombia, 2022)
Doença de Alzheimer
(Associação Brasileira de Psiquiatria - ABP, 1999-10-01)
This paper concisely reviews the genetics of Alzheimer Disease (AD). So far, three different genes have been implicated in AD. Specifically, the gene that codes for APP - the amyloid beta precursor protein, which is ...
Brain structural and amyloid correlates of recovery from semantic interference in cognitively normal individuals with or without gamily history of late-onset Alzheimer's disease
(American Psychiatric Association, 2019)
Abstract: Failure to recover from proactive semantic interference (frPSI) has been shown to be more sensitive than traditional cognitive measures in different populations with preclinical Alzheimer’s disease. The authors ...
Cortical thickness, brain metabolic activity, and in vivo amyloid deposition in asymptomatic, middle-aged offspring of patients with late-onset Alzheimer's disease
(Pergamon-Elsevier Science Ltd, 2018-12)
The natural history of preclinical late-onset Alzheimer's disease (LOAD) remains obscure and has received less attention than that of early-onset AD (EOAD), in spite of accounting for more than 99% of cases of AD. With the ...
Relationship between cognitive and sleep–wake variables in asymptomatic offspring of patients with late-onset alzheimer’s disease
(Frontiers Media, 2017)
Abstract: Early neuropathological changes characteristic of late-onset Alzheimer’s disease (LOAD) involve brain stem and limbic structures that regulate neurovegetative functions, including sleep–wake rhythm. Indeed, sleep ...
Targeting Neuroplasticity, Cardiovascular, and Cognitive-Associated Genomic Variants in Familial Alzheimer's Disease
(SpringerGrupo de Neurociencias de AntioquiaClifton, Estados Unidos, 2021)