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Impact of VDR and RXR expression in non-melanoma skin cancer pathogenesis
(2022-01-01)
1,25(OH)2D3, the active form of vitamin D, has been extensively studied for its putative protective activities against tumors. It does biological work by connecting to a nuclear receptor called VDR, which heterodimerizes ...
Genomic instability in human actinic keratosis and squamous cell carcinoma
(Faculdade de Medicina / USP, 2011)
OBJECTIVE: To compare the repetitive DNA patterns of human actinic keratoses and squamous cell carcinomas to determine the genetic alterations that are associated with malignant transformation. INTRODUCTION: Cancer cells ...
Accuracy of dermoscopic criteria for the differential diagnosis between irritated seborrheic keratosis and squamous cell carcinoma
(Elsevier, 2020)
Background: Even with the addition of dermoscopy, a significant morphologic overlap exists between irritated seborrheic keratosis (ISK) and squamous cell carcinoma (SCC).
Objective: The aim of this study was to investigate ...
Topical photodynamic therapy with methylaminolevulinate for the treatment of actinic keratosis and reduction of photodamage in organ transplant recipients: A case-series of 16 patients
(MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2012)
Background: Organ transplant recipients (OTR) are at high risk of developing cutaneous neoplasms. Topical photodynamic therapy (PDT) has been used for the treatment of actinic keratosis (AK) in OTR. Aims: The objective was ...
Retinoids for prevention and treatment of actinic keratosis
(Sociedade Brasileira de Dermatologia, 2013-08-01)
Actinic keratosis is a common cause of dermatological consultations and it presents a strong association with squamous cell carcinoma. Many substances are used for treatment and prevention, such as retinoids. Nevertheless, ...
Actinic keratosis: a clinical and epidemiological revision
(Sociedade Brasileira de Dermatologia, 2014)