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Ciprofloxacin in Layered Double Hydroxides: Looking for the Best Synthesis Method
(Elsevier, 2021-10-12)
It is important to develop new methods of release to improve pharmacokinetic parameters of drugs, especially antibiotics, whose plasmatic concentration is determinant to ensure an effective treatment. Layered double ...
PLGA based drug delivery systems (DDS) for the sustained release of insulin: Insight into the protein/polyester interactions and the insulin release behavior
(John Wiley & Sons Ltd, 2010-12)
BACKGROUND: Drug delivery systems (DDS) were designed using insulin as model drug and poly (lactic-co-glycolic) copolymers (PLGA) as polymeric matrix. The carriers were synthesized by direct self-assembly of the insulin ...
Synthesis of Layered Double Hydroxides Intercalated With Drugs for Controlled Release: Successful Intercalation of Ibuprofen and Failed Intercalation of Paracetamol
(Elsevier, 2021-04)
This work examines the effect of drug structure and ionization degree on the formation and properties of biocompatible layered double hydroxides (LDH) intercalated with ibuprofen and paracetamol. Ibuprofen (pKa = 5.3) is ...
Assessment of a modified release verapamil.HCl matrix compacts : Effect of formulation composition on the in-vitro release kinetic
(Academic JournalsDiseño y Formulación de Medicamentos Cosméticos y AfinesLagos, Nigeria, 2022)
One-dimensional drug release from finite Menger sponges: In silico simulation
(Pergamon-Elsevier Science Ltd, 2009-12)
The purpose of this work was to evaluate the consequences of the spatial distribution of components in pharmaceutical matrices type Menger sponge on the drug release kinetic from this kind of platforms by means of Monte ...
Multilayered electrospun nanofibrous scaffolds for tailored controlled release of embelin
(Taylor & Francis, 2018-01)
Polymeric electrospun meshes are highly attractive as versatile platforms for numerous biomedical applications, tissue engineering, biosensors, and controlled release of bioactive agents. Herein, we describe the preparation ...
Films based on soy protein-agar blends for wound dressing: Effect of different biopolymer proportions on the drug release rate and the physical and antibacterial properties of the films
(SAGE Publications, 2018-04)
No single material can provide all requirements for wound dressings. Here, we evaluated the influence of different soy protein isolate and agar proportions (3:1, 1:1, and 1:3) in blend films on some of their physical-chemical ...
Bioactive starch nanocomposite films with antioxidant activity and enhanced mechanical properties obtained by extrusion followed by thermo-compression
(Elsevier, 2019-11)
In this work bioactive starch films with antioxidant activity were developed by extrusion followed by thermo-compression. Rosemary extract was incorporated into starch-glycerol films in different concentrations (2.5%, 5% ...
Flavor release by enzymatic hydrolysis of starch samples containing vanillin-amylose inclusion complexes
(Elsevier Science, 2014-05)
Hylon VII is a high amylose corn starch which has excellent gelling properties, and its behavior as flavor encapsulant is relevant to the food industry because its ability to regulate a swelling-controlled release in aqueous ...
Kinetics of human sperm acrosomal exocytosis
(Oxford University Press, 2014-09-01)
The acrosome reaction is a unique event in the lifespan of sperm characterized by the exocytosis of the acrosomal content and the release of hybrid vesicles formed by patches of the outer acrosomal membrane and the plasma ...