Now showing items 31-40 of 442
CFTR modulates RPS27 gene expression using chloride anion as signaling effector
(Elsevier Science Inc, 2017-09)
In Cystic Fibrosis (CF), the impairment of the CFTR channel activity leads to a variety of alterations, including differential gene expression. However, the CFTR signaling mechanisms remain unclear. Recently, culturing ...
IKK connects autophagy to major stress pathways
(Taylor and Francis Inc., 2010)
Cells respond to stress by activating cytoplasmic mechanisms as well as transcriptional programs that can lead to adaptation or death. Autophagy represents an important cytoprotective response that is regulated by both ...
The role of the B7-1/2, LFA-3 and ICAM-1 costimulatory molecules in the modulation of T cell responses
The physiological activation of T cells to proliferation and cytokine production requires at least two signals. Occupancy of the T cell receptor by antigen/MHC complexes delivers the first signal to T cell, while the second ...
Angiotensin II-induced JNK activation is mediated by NAD(P)H oxidase in isolated rat pancreatic islets
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Angiotensin II (All), the active component of the renin angiotensin system (RAS), plays a vital role in the regulation of physiological processes of the cardiovascular system, but also has autocrine and paracrine actions ...
P75 NEUROTROPHIN RECEPTOR-MEDIATED APOPTOSIS IN SYMPATHETIC NEURONS INVOLVES A BIPHASIC ACTIVATION OF JNK AND UP-REGULATION OF TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME/ADAM17
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2010)