Now showing items 11-20 of 442
Low salt intake modulates insulin signaling, JNK activity and IRS-1(ser307) phosphorylation in rat tissues
(Soc EndocrinologyBristolInglaterra, 2005)
Modulation of the response of prostate cancer cell lines to cisplatin treatment using small interfering RNA
Cisplatin is one of the most effective and widely used chemotherapeutic agents against several types of human cancers. However, the underlying mechanisms of action are not fully understood. We aimed to investigate the ...
Increased expression of p21Waf1/Cip1 and JNK with costimulation of prostate cancer cell activation by an siRNA Egr-1 inhibitor
The p21Waf1/Cip1 protein (hereafter, p21) and the c‑Jun N-terminal kinase (JNK) are two well-characterized cell modulators that play a crucial role in cell differentiation, senescence and apoptosis. Here, we report that ...
17β-estradiol abrogates apoptosis inhibiting PKCδ, JNK and p66Shc activation in C2C12 cells
17β-Estradiol (E2) protects several non-reproductive tissues from apoptosis, including skeletal muscle. Previously, we showed that E2 at physiological concentrations prevented apoptosis induced by H2O2 in skeletal myoblasts. ...
c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway
(WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-02-15)
In this study, we demonstrated that tyrosine phosphorylation of EGFR and the autocrine expression of uPA and HB-EGF depend on the activity of c-jun amino-terminal kinase (JNK) in human prostatic DU-145 cells. These cells ...
DEFECT IN ERK2 AND P54(JNK) ACTIVATION IN AGING MOUSE SPLENOCYTES
(GERONTOLOGICAL SOCIETY OF AMERICA, 2002)
MODULATION OF THE JNK AND P38 PATHWAYS BY CDK5 PROTEIN KINASE IN A TRANSGENIC MOUSE MODEL OF ALZHEIMERS DISEASE
(LIPPINCOTT WILLIAMS & WILKINS, 2003)
JNK MEDIATES TGF-BETA 1-INDUCED EPITHELIAL MESENCHYMAL TRANSDIFFERENTIATION OF MOUSE TRANSFORMED KERATINOCYTES
(ELSEVIER SCIENCE PUBLISHERS B.V., 2006)