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Levels of interleukin-21 in patients with untreated chronic periodontitis
(American Academy of Periodontology, 2011-10)
BACKGROUND: A growing body of evidence suggested that interleukin (IL)-21 enhances the effector phase during T-cell responses. The aim of our study is to determine the levels of IL-21 in periodontal sites from patients ...
Use of human mesenchymal cells to improve vascularization in a mouse model for scaffold-based dermal regeneration
(Mary Ann Liebert, 2009)
All engineered bioartificial structures developed for tissue regeneration require oxygen and nutrients to establish proper physiological functions. Aiming to improve vascularization during dermal regeneration, we combined ...
Physiologic activation of nuclear factor kappa-B in the endometrium during the menstrual cycle is altered in endometriosis patients
(Elsevier, 2012-03)
Objective: To evaluate nuclear factor kappaB (NF-kB) activation and NF-kB–p65 subunit activation, immunolocalization, and expression in the endometrium
of healthy women and endometriosis patients throughout the menstrual ...
Compensatory kidney hypertrophy/hyperplasia after nephrectomy in mice: alterations of connexin 43 (Cx43) phosphorylated isoforms
(Botucatu, 2008)
Compensatory kidney hypertrophy/hyperplasia leads to several changes in kidney structure and function, as increased glomeruli filtration. The aim of this study was to evaluate connexin 43 in remnant mouse kidneys after ...
Study of PI3K/AKT/mTOR pathway in breast cancer progression
(Instituto de Histología y Embriología, 2018)
Deregulation in the PI3K/AKT/mTOR pathway is associated with breast cancer development. Using experimental models of breast carcinogenesis induced in mice, xenografts of tumor cell lines, and tumors from patients we found ...
Glucose, amino acids and fatty acids directly regulate ghrelin and NUCB2/nesfatin-1 in the intestine and hepatopancreas of goldfish (Carassius auratus) in vitro
(Elsevier Science Inc, 2017-04)
Ghrelin and nesfatin-1 are two peptidyl hormones primarily involved in food intake regulation. We previously reported that the amount of dietary carbohydrates, protein and lipids modulates the expression of these peptides ...
Death receptor and mitochondrial pathways are involved in germ cell apoptosis in an experimental model of autoimmune orchitis
(Oxford University Press, 2006-12)
Background: Studies on experimental autoimmune orchitis (EAO) have helped to elucidate immunological mechanisms involved in testicular damage. We previously demonstrated that EAO is characterized by lymphomononuclear cell ...
Quantitative real-time RT-PCR and chromogenic in situ hybridization: precise methods to detect HER-2 status in breast carcinoma
(Biomed Central Ltd., 2009-03-23)
Background: HER-2 gene testing has become an integral part of breast cancer patient diagnosis. The most commonly used assay in the clinical setting for evaluating HER-2 status is immunohistochemistry (IHC) and fluorescence ...
Microvascular lesions and changes in cell proliferation and death, and cytokine expression in the placentas of mice experimentally infected with Equid Herpesvirus 1
(Elsevier, 2016-12)
This study describes the changes observed in the placentas of mice experimentally infected with an abortigenic strain of EHV-1 at mid-pregnancy and euthanized at days 3 and 4 post-infection. We analyzed microscopic vascular ...
Relationship between plasma cells and hepatic stellate cells in autoimmune hepatitis
(ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2010)
Autoimmune hepatitis is an inflammatory chronic disease of the liver, which frequently results in cirrhosis. The present study aimed to verify the relationship between plasma cells and stellate cells in autoimmune hepatitis. ...