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Igf2 And Igf1r In Pediatric Adrenocortical Tumors: Roles In Metastasis And Steroidogenesis
(Bioscientifica LtdBristol, 2016)
Investigation of IGF2/ApaI and H19/RsaI polymorphisms in patients with cutaneous melanoma
(CHURCHILL LIVINGSTONE, 2010)
Objective: The etiology of cutaneous melanoma is complex, involving both heterogeneous genetic and environmental components. The aim of our study was to verify if single polymorphic sites within IGF2 and H19 genes and their ...
Circulating IGF-I, IGFBP-3 and the IGF-I/IGFBP-3 Molar Ratio Concentration and Height Outcome in Prepubertal Short Children on rhGH Treatment over Two Years of Therapy
(Karger, 2017-03)
Objective: To investigate the occurrence of abnormally elevated values of biomarkers of growth hormone (GH) action in short children on recombinant human GH (rhGH) therapy. Methods: Sixty-three prepubertal short children ...
IGF1 regulation of BOULE and CDC25A transcripts via a testosterone-independent pathway in spermatogenesis of adult mice
(Inst Animal Reproduction Food Research, 2015-03)
The Deleted in AZoospermia (. DAZ) gene family plays an essential role in spermatogenesis and fertility in mammals. This gene family contains two autosomal genes, BOULE and DAZL (. DAZ-. Like), and the DAZ gene cluster in ...
Altered liver expression of genes involved in lipid and glucose metabolism in mice with partial IGF-1 deficiency: an experimental approach to metabolic syndrome
(Springer Open, 14/10/2015)
Abstract Background Insulin growth factor 1 (IGF-1) has multiple effects on metabolism. Much evidence suggests that the deficiency of this hormone increases insulin resistance, impairs lipid metabolism, augments oxidative ...
Caracterización del sistema de los factores de crecimiento similares a la insulina (IGFs) en el establecimiento del feocromocitoma y en la progresión de tumores de sistema nervioso central (SNC) en pacientes pediátricos
(2019-03-12)
La carcinogénesis es un proceso de múltiples pasos por el cual células normales se transforman en células tumorales. Las señales que facilitan estos procesos están lideradas en su mayoría por factores de crecimiento que ...
Leptin and IGF1 receptors in alpaca (Vicugna pacos) ovaries
(Elsevier Science, 2019-01)
Folliculogenesis and ovulation are regulated by gonadotrophins and other factors such as Insulin like growth factor 1 (IGF1) and leptin. In various species the presence of IGF1 receptor (IGF1R) and leptin receptor (ObR) ...
Augmented serum levels of the IGF-I/IGFBP3 ratio in pre-menopausal patients with type I breast cysts
(BioScientifica, 2003-02)
Gross cystic disease (GCD) is the most common benign breast pathology. Although breast cysts are not considered pre-malignant lesions, an increased risk of breast cancer has been reported for patients with type I cysts ...