Now showing items 31-40 of 1254
Thermoprotective effect of insulin-like growth factor 1 on in vitro matured bovine oocyte exposed to heat shock
(Elsevier B.V., 2016-11-01)
The role of insulin-like growth factor 1 (IGF1) on cellular function and developmental capacity of heat-shocked oocytes has not been completely understood. Therefore, the objective of this study was to determine the effect ...
Effects of swimming training on bone mass and the GH/IGF-1 axis in diabetic rats
(Churchill Livingstone, 2006-10-01)
The aim of this study was to examine the influence of moderate swimming training on the GH/IGF-1 growth axis and tibial mass in diabetic rats. Male Wistar rats were allocated to one of four groups: sedentary control (SC), ...
Imprinted gene expression in in vivo- and in vitro-produced bovine embryos and chorio-allantoic membranes
Cloning by nuclear transfer is often associated with poor results due to abnormal nuclear reprogramming of somatic donor cells and altered gene expression patterns. We investigated the expression patterns of imprinted genes ...
Papel del sistema de factores de crecimiento similares a la insulina (IGF) en la regulación del crecimiento y diferenciación trofoblástica
Durante la diferenciación trofoblástica la expresión de genes y secreción de proteínas como la hormona Gonadotropina Coriónica humana (hCG) cambia; no obstante, el mecanismo molecular del proceso aún no es claro. Así mismo, ...
Diabetes-associated changes in the fetal insulin/insulin-like growth factor system are organ specific in rats
(Nature Publishing Group, 2015-01)
Background: Diabetes in pregnancy affects fetal growth and development. The insulin/insulin-like growth factors (IGF) system comprising insulin, IGF, their receptors, and binding proteins, has been implicated in fetal ...
The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009-10-09)
Myocyte enhancer factor 2C (MEF2C) plays an important role in cardiovascular development and is a key transcription factor for cardiac hypertrophy. Here, we describe MEF2C regulation by insulin-like growth factor-1 (IGF-1) ...
IGF-IR signal transduction protein content and its activation by IGF-I in human placentas: relationship with gestational age and birth weight
(PLOS One, 2014)
Introduction: The human placenta expresses the IGF-I and IGF-IR proteins and their intracellular signal components (IRS-1, AKT and mTOR). The aim of this study was to assess the IGF-IR content and activation of downstream ...
Igf2 And Igf1r In Pediatric Adrenocortical Tumors: Roles In Metastasis And Steroidogenesis
(Bioscientifica LtdBristol, 2016)
Investigation of IGF2/ApaI and H19/RsaI polymorphisms in patients with cutaneous melanoma
(CHURCHILL LIVINGSTONE, 2010)
Objective: The etiology of cutaneous melanoma is complex, involving both heterogeneous genetic and environmental components. The aim of our study was to verify if single polymorphic sites within IGF2 and H19 genes and their ...