Now showing items 21-30 of 88
Immunostimulatory activity of low-molecular-weight hyaluronan on dendritic cells stimulated with Aggregatibacter actinomycetemcomitans or Porphyromonas gingivalis
OBJECTIVES: Periodontitis is a chronic inflammatory disease characterized by tooth-supporting tissue destruction, which is elicited by the host's immune response triggered against periodonto-pathogen bacteria. During ...
Novel bioadhesive hyaluronan-itaconic acid crosslinked films for ocular therapy
(Elsevier Science, 2013-08)
New hyaluronic acid (HA)–itaconic acid (IT) films have been previously synthesized and used as potential topical drug delivery systems (DDS) for ocular administration. In this study we explored homogeneous and heterogeneous ...
Hyaluronan involvement in the changes of mouse interpubic tissue during late pregnancy and post-partum
(Academic Press Ltd Elsevier Science LtdLondonInglaterra, 2008)
Hyaluronan as drug carrier. The in vitro efficacy and selectivity of Hyaluronan-Doxorubicin complexes to affect the viability of overexpressing CD44 receptor cells
(Elsevier Science, 2014-09)
We report Doxorubicin ionic complexes with hyaluronic acid (HiH-Dx) or its sodium salt (HiNa-Dx) as tumor-targeting delivery system. The complexes were prepared in situ by mixing aqueous solutions of Dx.HCl with HiH or ...
Low Molecular Weight Hyaluronan-Pulsed Human Dendritic Cells Showed Increased Migration Capacity and Induced Resistance to Tumor Chemoattraction
(Public Library of Science, 2014-09)
We have shown that ex vivo pre-conditioning of bone marrow-derived dendritic cells (DC) with low molecular weight hyaluronan (LMW HA) induces antitumor immunity against colorectal carcinoma (CRC) in mice. In the present ...
Isoforms of hyaluronidases can be a predictor of a prostate cancer of good prognosis
(ELSEVIER SCIENCE INC, 2009)
Introduction: Hyaluronidases (HAases) are enzymes related to cancer progression. Isoforms of HAases have been described as products of alternative splicing responsible for differences in enzyme activity. The heterogeneity ...
Hyaluran-itaconic acid-glutaraldehyde films for biomedical applications: Preliminary studies
New hyaluronic acid?itaconic acid films were synthesized as potential materialswith biomedical applications. In this work, we explored the homogeneous crosslinkingreactions of hyaluronic acid using glutaraldehyde in the ...
Experimental tendon repair: Glycosaminoglycan arrangement in newly synthesized collagen fibers
(Cellular & Molecular BiologyNoisy-le-grandFrança, 2003)