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SICKLE-CELL DISEASE IN A BRAZILIAN POPULATION FROM SAO-PAULO - A STUDY OF THE BETA(S) HAPLOTYPES
(KargerBaselSuíça, 1994)
Functional haplotype in the Interleukin8 (CXCL8) gene is associated with type 2 Diabetes Mellitus and Periodontitis in Brazilian population
(2020-11-01)
Background and aim: Type 2 Diabetes Mellitus (T2DM) and Periodontitis (P) are prevalent multifactorial disorders worldwide, sharing a bidirectional relationship influenced by the genetic susceptibility of the host immune ...
Haplotype-based gene–gene interaction of bone morphogenetic protein 4 and interferon regulatory factor 6 in the etiology of non-syndromic cleft lip with or without cleft palate in a Chilean population
(Blackwell Munksgaard, 2017)
© 2017 Eur J Oral Sci Non-syndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect in humans, the etiology of which can be dependent on the interactions of multiple genes. We ...
A phased SNP-based classification of sickle cell anemia HBB haplotypes
(Biomed Central Ltd, 2017)
Background: Sickle cell anemia causes severe complications and premature death. Five common beta-globin gene cluster haplotypes are each associated with characteristic fetal hemoglobin (HbF) levels. As HbF is the major ...
HLA-G, -E and -F regulatory and coding region variability and haplotypes in the Beninese Toffin population sample
(2018-12-01)
HLA-G/E/F genes exhibit immunomodulatory properties and are expressed in placenta. Little attention has been devoted to the study of these genes in sub-Saharan African populations, which are yet the most diverse. To fill ...
Plasma matrix metalloproteinase-9 levels, MMP-9 gene haplotypes, and cardiovascular risk in obese subjects
(2016-06-01)
Plasma matrix metalloproteinase (MMP)-9 is a predictor of cardiovascular mortality, and MMP-9 polymorphisms affect plasma MMP-9 levels. However, no study examined whether MMP-9 haplotypes affect MMP-9 levels in obese adults. ...
Comparison of ovine β-globin haplotype sequences and a new multiplex PCR for identification
(2021-12-01)
Deletion of pre-adult βC-globin in sheep harboring BB haplotype of β-globin was associated to decreased tolerance to anemia and hypoxia, and consequently, reduced resistance to Haemonchus contortus infection, which is ...
Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project
(Springer, 2008-01)
The human major histocompatibility complex (MHC) is contained within about 4 Mb on the short arm of chromosome 6 and is recognised as the most variable region in the human genome. The primary aim of the MHC Haplotype Project ...