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Mostrando ítems 11-20 de 42
Determination of cell-surface hyaluronan through flow cytometry
(Humana Press, 2019)
Hyaluronan is the major glycosaminoglycan present in the extracellular matrix of several cell types; its synthesis occurs on the cellular plasma membrane. Variations in its expression are related to alterations in cell ...
The immunological effect of hyaluronan in tumor angiogenesis
(Springer Nature, 2015-12)
The relationship between the immune system and angiogenesis has been described in several contexts, both in physiological and pathological conditions, as pregnancy and cancer. In fact, different types of immune cells, such ...
Towards efficient biocatalysts: photo-immobilization of a lipase on novel lysozyme amyloid-like nanofibrils
(Royal Society of Chemistry, 2016-01)
Herein, we report the preparation and characterization of a new biocatalyst based on the photo-immobilization of a lipase onto hybrid protein : sugar nanofibrils. The nanofibrils are obtained through the aggregation of hen ...
Towards efficient biocatalysts: Photo-immobilization of a lipase on novel lysozyme amyloid-like nanofibrils
(Royal Society of Chemistry, 2016-01)
Herein, we report the preparation and characterization of a new biocatalyst based on the photo-immobilization of a lipase onto hybrid protein:sugar nanofibrils. The nanofibrils are obtained through the aggregation of hen ...
The Role of the Tumor Microenvironment in the Development and Progression of Hepatocellular Carcinoma
(Codon Publications, 2019)
There is a growing evidence that supports the role of the tumor microenvironment (TME) in the development and progression of cancer. TME is composed of cellular components, bioactive substances (e.g. growth factors) and ...
Biocompatible hydrogel for intra-articular implantation comprising cationic and anionic polymers of natural origin: In vivo evaluation in a rabbit model
(MDPI, 2021-12)
We describe the functional capability of a cross-linked hydrogel composed of sulfated glycosaminoglycans and a cationic cellulose by conducting trials on experimental animal models using intra-articular implants to treat ...
The scrambled story between hyaluronan and glioblastoma
(American Society for Biochemistry and Molecular Biology, 2021-01)
Advances in cancer biology are revealing the importance of the cancer cell microenvironment on tumorigenesis and cancer progression. Hyaluronan (HA), the main glycosaminoglycan in the extracellular matrix, has been associated ...
Structural Characterization of Heparin-induced Glyceraldehyde-3-phosphate Dehydrogenase Protofibrils Preventing α-Synuclein Oligomeric Species Toxicity
(American Society for Biochemistry and Molecular Biology, 2014-03)
Background:Although glycosaminoglycan-induced GAPDH prefibrillar species accelerates -synuclein aggregation, itsrole in toxicity remains unclear.Results:The toxic effect exerted by -synuclein oligomers on cell culture was ...
Vicuna oviduct mucosa: Ultrastructure and lectin affinity
(Elsevier Science, 2006-12)
The isthmus and uterotubal junction (UTJ) from oviducts of adult female vicunas (Vicugna vicuna) were used to study the epithelial cell ultrastructure. Scanning microphotographs revealed a mosaic pattern made up of ciliated ...