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Mostrando ítems 1171-1180 de 2565
LRRK-2 as a Key Molecule Bridging Inflammation to Parkinson's Disease
(IOS Press, 2013-11)
The pathogenetic mechanisms leading to typical Parkinson's Disease (PD), the second most common human neurodegenerative disorder remains unknown. Genetic variants of Leucine-Rich Repeat Kinase 2 (LRRK-2) are associated ...
Homocystinuria, Case ReportHomocistinuria, reporte de un casoHomocistinúria, relato de um caso
(Universidad Militar Nueva Granada, 2020)
Candidate gene discovery in autoimmunity by using extreme phenotypes, next generation sequencing and whole exome capture
Whole exome sequencing (WES) is a widely used strategy for detection of protein coding and splicing variants associated with inherited diseases. Many studies have shown that the strategy has been broad and proficient due ...
Identificación de deleciones en portadoras de distrofia muscular de Duchenne
Objectives: identification of carrier women in families affected with Duchenne’s and Becker’s Muscular Dystrophy (DMD/DMB) by means of Haplotypes building and the determination of loss of heterocygocity. Introduction: ...
Teneurins: An Integrative Molecular, Functional, and Biomedical Overview of Their Role in Cancer.
(2018)
Teneurins are large transmembrane proteins originally identified in Drosophila. Their essential role in development of the central nervous system is conserved throughout species, and evidence supports their involvement in ...
Reproductive and metabolic features during puberty in sons of women with polycystic ovary syndrome
(2017)
Context: Intrauterine life may be implicated in the origin of polycystic ovary syndrome (PCOS) modifying the endocrine and metabolic functions of children born to PCOS mothers independently of the genetic inheritance and ...
Aspectos básicos da fisiopatologia e de cuidados às pessoas portadoras de doença falciforme
(Universidade Federal de Minas GeraisUFMG, 2013-08-03)
Sickle cell disease is a structural hemoglobinopathy, being one of the most common inherited diseases in Brazil and worldwide, with dominant character, transmitted from parents to children. Its historical-geographical ...
Manifestações bucais da anemia falciforme: abordagem ao paciente pelo cirurgião-dentista
(Universidade Federal de Minas GeraisUFMG, 2011-12-10)
This study talks about the issue of oral manifestations of sickle cell anemia and management of patients by dentists in primary care. The central objective is the knowledge of the main oral manifestations of the disease ...
The bacterial chromosome segregation protein Spo0J spreads along DNA from parS nucleation sites
(Blackwell Publishing, 2006-09-01)
Regulation of chromosome inheritance is essential to ensure proper transmission of genetic information. To accomplish accurate genome segregation, cells organize their chromosomes and actively separate them prior to ...
Índice de seleção bioeconômico para fêmeas de corte da raça nelore
(2012-12-01)
The reproductive efficiency of Nellore females was described on the basis of sexual precocity, staying productive in the herd (NP), maternal productivity (PM) and estimated cost for maintenance (CM). The combination of ...