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Sobreexpresión de TRPM4 y KCTD5 como biomarcadores de cáncer de mama triple negativo
(Universidad de Chile, 2019)
El cáncer de mama es una de las principales afecciones en mujeres chilenas, afectando a 32/100.000 mujeres y con una tasa de mortalidad de 14,5, lo que vuelve necesario la búsqueda de mejoras en la detección e identificación ...
Sinalização do hormônio tireoideano no cérebro de camundongos após status epilepticus induzido por Pilocarpina
(Universidade Federal de São Paulo (UNIFESP), 2016-11-30)
Thyroid hormones play an important role in the development and maintenance of Central Nervous System through the control of gene expression. Although serum concentration of TH is remarkably stable, deiodinases regulate ...
Papel do fator de transcrição ikaros na via de sinalização do receptor de célula b em pacientes com leucemia linfocítica crônica.
(Universidade Federal de São Paulo (UNIFESP), 2018-08-01)
Introduction: Chronic Lymphocytic Leukemia (CLL) is characterized by the
clonal proliferation of mature B-lymphocytes. It is the most common form of
leukemia in Western countries, and usually affects older individuals. ...
Busca por miRNAs provenientes de exossomos relevantes para epileptogênese
(Universidade Federal de São Paulo, 2022)
O Traumatismo Cranioencefálico (TCE) é altamente frequente no Brasil, ocorrendo mais de 150 mil casos por ano, e é um grande fator de risco para o desenvolvimento de epilepsia pós-traumática (EPT). Contudo, o tratamento ...
Modulação da expressão de proteínas relacionadas a via de apresentação de antígenos pelo MHC classe I em células após a infecção por citomegalovírus
(Universidade Federal de São Paulo (UNIFESP), 2021)
The major histocompatibility complex (MHC) is a group of proteins important for immunity, autoimmunity and tissue recognition. Its main function is recognize and present self or nonself antigens (peptides) for the adaptive ...
Determinación de anomalías cromosómicas y secuencias de ADN amplificadas en cáncer de mama
(Universidad del RosarioEscuela de Medicina y Ciencias de la Salud, 2010)
Breast cancer is the third cause of death in the general population and the second one in Colombian women. In 2002, 40.5% of the cases were of women younger than 50. Breast cancer originates as a result of multiple and ...
Efecto de la modulación de PPARy sobre la vía reversa del colesterol
(MedUNAB, 2006-10-26)
Introduction: Nuclear receptor LXRα (liver X receptor alpha) has a beneficial effect on the reverse pathway of cholesterol and reverts some defects in the lipid metabolism that are related with cardio-vascular risk. LXRα ...
An integrative analysis of post-translational histone modifications in the marine diatom Phaeodactylum tricornutum
(BioMed Central, 2015-05)
Background: Nucleosomes are the building blocks of chromatin where gene regulation takes place. Chromatin landscapes have been profiled for several species, providing insights into the fundamental mechanisms of chromatin-mediated ...
Transcriptomic profile of two developmental stages of the cestode parasite Mesocestoides corti
(Elsevier Science, 2019-04)
Cestode development involves complex morphological and physiological changes. Here, we performed a differential expression analysis of gene transcripts between two developmental stages of the model cestode Mesocestoides ...
Inactivation of farR Causes High Rhodomyrtone Resistance and Increased Pathogenicity in Staphylococcus aureus
(Frontiers Media S.A., 2019-05)
Rhodomyrtone (Rom) is an acylphloroglucinol antibiotic originally isolated from leaves of Rhodomyrtus tomentosa. Rom targets the bacterial membrane and is active against a wide range of Gram-positive bacteria but the exact ...