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TRPC1 regulates calcium-activated chloride channels in salivary gland cells
(Wiley-liss, Div John Wiley & Sons Inc, 2015-11)
Calcium-activated chloride channel (CaCC) plays an important role in modulating epithelial secretion. It has been suggested that in salivary tissues, sustained fluid secretion is dependent on Ca2+ influx that activates ion ...
Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome
(Elsevier, 2014-02)
Ultraviolet (UV)-induced DNA damage are removed by nucleotide excision repair (NER) or can be tolerated by specialized translesion synthesis (TLS) polymerases, such as Polη. TLS may act at stalled replication forks or ...
Physicochemical, interfacial and emulsifying properties of a non-conventional exudate gum (Prosopis alba) in comparison with gum arabic
(Elsevier, 2016-05)
Physicochemical and emulsifying properties of a novel exudate gum from Prosopis alba (G) were assessed in comparison with the well-known arabic gum (GA). Compositional analysis, intrinsic viscosity and structural ...
Quantifying genetic diversity: the starting point for population genetic studies using molecular markers
(Indian Academy of Sciences, 2014-10)
Natural populations must keep genetic diversity since it is essential for the long-term survival of species and provides the raw material for all evolutionary changes.The emergence of marker systems has, for the last 40 ...
Classical and non-classical thyroid hormone intracellular pathways involved in T lymphoma growth
(Bentham Science Publishers, 2015-04)
Thyroid hormones (THs) are important regulators of cell physiology. They are essential for the normal development and growth of mammals, especially for the neural differentiation and the regulation of the metabolism and ...
Sodium/iodide Symporter Mutant V270E causes stunted growth but no cognitive deficiency
(Endocrine Society, 2015-10-01)
Iodide (I−), an essential constituent of the thyroid hormones, is actively accumulated in the thyroid by the Na+/I− symporter (NIS), a key plasma membrane protein encoded by the slc5a5 gene. Mutations in slc5a5 cause I− ...
CRISP1 as a novel CatSper regulator that modulates sperm motility and orientation during fertilization
(Rockefeller Univ Press, 2015-07)
Calcium-dependent mechanisms are critical for successful completion of fertilization. Here, we demonstrate that CRISP1, a sperm protein involved in mammalian fertilization, is also present in the female gamete and capable ...
RIMA-Dependent Nuclear Accumulation of IYO Triggers Auxin-Irreversible Cell Differentiation in Arabidopsis
(American Society of Plant Biologist, 2017-02)
The transcriptional regulator MINIYO (IYO) is essential and rate-limiting for initiating cell differentiation in Arabidopsis thaliana Moreover, IYO moves from the cytosol into the nucleus in cells at the meristem periphery, ...
Nutritional Composition of Opuntia sulphurea G. Don Cladodes
(Cactus and Succulent Society of America, 2014-03)
Several studies have shown the interesting properties of Opuntia spp. (“prickly pears”), although most of this knowledge is based on O. ficus-indica. O. sulphurea is a species that is largely distributed in the Monte region ...
Enhancement of Th1 immune responses to recombinant influenza nucleoprotein by Ribi adjuvant
(Luigi Ponzio e Figlio Editori, 2013-02)
A broad coverage influenza vaccine against multiple viral strains based on the viral nucleoprotein (NP) is a goal pursued by many laboratories. If the goal is to formulate the vaccine with recombinant NP it is essential ...