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Now showing items 2961-2970 of 5014
Nutrition Therapy in a Pediatric Intensive Care Unit: Indications, Monitoring, and Complications
(SAGE PUBLICATIONS INC, 2011)
Background: Nutrition therapy (NT) is essential for the care of critically ill children. Inadequate feeding leads to malnutrition and may increase the patient`s risk of morbidity and mortality. The aim of this study was ...
Identification of three distinguishable phenotypes in golden retriever muscular dystrophy
(FUNPEC-EDITORA, 2009)
Duchenne muscular dystrophy (DMD) is a human disease characterized by progressive and irreversible skeletal muscle degeneration caused by mutations in genes coding for important muscle proteins. Unfortunately, there is no ...
Relationship Between Expression of Voltage-Dependent Anion Channel (VDAC) Isoforms and Type of Hexokinase Binding Sites on Brain Mitochondria
(HUMANA PRESS INC, 2010)
Voltage-dependent anion channels (VDAC) are pore-forming proteins found in the outer mitochondrial membrane of eukaryotes. VDACs are known to play an essential role in cellular metabolism and in early stages of apoptosis. ...
Biological effects of insulin on murine melanoma cells and fish erythrophoroma cells: A comparative study
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
Insulin is the hormone that plays an essential role in metabolism and mitosis of normal and tumor cells, exerting its pleiotropic effects through binding to specific membrane receptors and promoting the phosphorylation of ...
Effects of let-7 microRNA on Cell Growth and Differentiation of Papillary Thyroid Cancer
(NEOPLASIA PRESS, 2009)
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy and RET/PTC rearrangements represent key genetic events frequently associated to this cancer, enhancing proliferation and dedifferentiation by ...
Next Generation Sequencing of Pooled Samples Reveals New SNRNP200 Mutations Associated with Retinitis Pigmentosa
(WILEY-BLACKWELL, 2011)
The gene SNRNP200 is composed of 45 exons and encodes a protein essential for pre-mRNA splicing, the 200 kDa helicase hBrr2. Two mutations in SNRNP200 have recently been associated with autosomal dominant retinitis pigmentosa ...
Biochemical characterization of serine transport in Leishmania (Leishmania) amazonensis
(ELSEVIER SCIENCE BV, 2009)
In addition to its role as a protein component in Leishmania, serine is also a precursor for the synthesis of both phosphatidylserine, which is a membrane molecule involved in parasite invasion and inactivation of macrophages, ...
REACTIVE OXYGEN SPECIES AND THE STRUCTURAL REMODELING OF THE VISUAL SYSTEM AFTER OCULAR ENUCLEATION
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Redox processes associated with controlled generation of reactive oxygen species (ROS) by NADPH oxidase (Nox) add an essential level of regulation to signaling pathways underlying physiological processes. We evaluated the ...
Multiple stages of detergent-erythrocyte membrane interaction-A spin label study
(ELSEVIER SCIENCE BV, 2011)
The various stages of the interaction between the detergent Triton X-100 (TTX-100) and membranes of whole red blood cells (RBC) were investigated in a broad range of detergent concentrations. The interaction was monitored ...
Functional Analysis of saxophone, the Drosophila Gene Encoding the BMP Type I Receptor Ortholog of Human ALK1/ACVRL1 and ACVR1/ALK2
(GENETICS SOC AM, 2009)
In metazoans, bone morphogenetic proteins (BMPS) direct a myriad of developmental and adult homeostatic evens through their heterotetrameric type I and type II receptor complexes. We examined 3 existing and 12 newly generated ...