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Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
(BioMed Central Ltd., 2014-01-01)
Background: RNA post-transcriptional modification is an exciting field of research that has evidenced this editing process as a sophisticated epigenetic mechanism to fine tune the ribosome function and to control gene ...
Entinostat (SNDX-275) for the treatment of non-small cell lung cancer
(Taylor and Francis, 2015)
INTRODUCTION: Epigenetic aberrations play an important role in lung carcinogenesis. Chromatin deacetylation is a fundamental mechanism of gene silencing. Histone deacetylase (HDAC) inhibitors are an emerging class of ...
Epigenetic Processes as Evolutionary Advanced Molecular Mechanisms to Cope with the Continuous Interaction Between DNA and the Environment
(American Scientific Publishers, 2009-06)
The traditional concept that the phenotype of an organism is the resultant of the genetic code and the influence from the environment has recently acquired implications not previously suspected. Evidence has been accumulating ...
JMJD1A, H3K9me1, H3K9me2 and ADM expression as prognostic markers in oral and oropharyngeal squamous cell carcinoma
(Public Library of Science, 2018-03-28)
Microbiota, epigenética y respuesta a medicamentos en el cáncer de colon
(2020-10-16)
El cáncer de colon es una de las principales causas de muerte a nivel mundial, en este sentido, a pesar de que se ha reducido la tasa de mortalidad, la incidencia en pacientes jóvenes sigue aumentando. El presente trabajo ...