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Involvement of GABAB receptors in biochemical alterations induced by anxiety-related responses to nicotine in mice: Genetic and pharmacological approaches
(Elsevier, 2014-01)
Previous studies from our laboratory showed that anxiety-related responses induced by nicotine (NIC), measured by the elevated plus maze, were abolished by 2-OH-saclofen (GABAB receptor antagonist) (1 mg/kg; ip) or the ...
Previous stress exposure enhances both anxiety-like behaviour and p35 levels in the basolateral amygdala complex: Modulation by midazolam
(Elsevier Science, 2010-06)
Stress exposure induces long lasting neurobiological changes in selected brain areas, which could be associated with the emergence of negative emotional responses. In the present study, previously restrained animals exhibited ...
Histaminergic systems of the limbic complex on learning and motivation
(Elsevier Science, 2001-10)
The possible role of histamine sensitive sites in hippocampus and the nucleus accumbens on memory and exploratory motivation was studied. As a model of memory, the learning of an active avoidance response to an ultrasonic ...
Early prenatal exposure to LPS results in anxiety- and depression-related behaviors in adulthood
(Pergamon-Elsevier Science Ltd, 2015-07)
Maternal immune activation can result in different behavioral abnormalities and brain dysfunction, depending on the nature of the inflammogen and the timing of the challenge. Few studies report the possible link between ...
Behavioral effects of the combined use of alcohol and energy drinks on alcohol hangover in an experimental mice model
(Elsevier Ireland, 2018-03)
In last few years it has been a significant increase in the consumption of alcohol combined with energy drink. The aim of this work was to study the effect of this mixture in motor and affective behaviors during an alcohol ...
Long-term impact of chronic variable stress in adolescence versus adulthood
(Pergamon-Elsevier Science Ltd, 2019-01)
Adolescence is a period of active development of stress regulatory neurocircuitry. As a consequence, mechanisms that control the responses to stress are not fully matured during this developmental period, which may result ...
Resistance to fear memory destabilization triggers exaggerated emotional-like responses following memory reactivation
(Pergamon-Elsevier Science Ltd, 2019-07)
Fear memory reactivation does not always lead to memory destabilization-reconsolidation. For instance, fear memories formed following withdrawal from chronic ethanol consumption or a stressful event are less likely to ...
Sex differences in rats: Effects of chronic stress on sympathetic system and anxiety
(Pergamon-Elsevier Science Ltd, 2005-06)
In this study we tested whether periodic maternal deprivation (MD) (4.5 h daily during the first 3 weeks of life) caused chronic changes in anxiety and medullo-adrenal responses to chronic stress in either male or female ...
Transient serotonin depletion at adolescence, but not at early infancy, reduced subsequent anxiety-like behavior and alcohol intake in female mice
(Springer, 2021-01)
Serotonin (5-HT) plays an important role in the organization of the central nervous system and in the development of social interaction deficits and psychiatric disorders, including anxiety, depression, and addiction ...
Functional lateralization of the baso-lateral amygdala neural circuits modulating the motivated exploratory behaviour in rats: Role of histamine
(Elsevier Science, 2011-03)
Functional laterality appears to be present in many brain functions in man and animals. The existence of paired neural circuits which act differentially to modulate a specific behavioural function seems to be an evolutionary ...