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Detailed characterization of the cooperative binding of piperine with heat shock protein 70 by molecular biophysical approaches
(2020-12-01)
In this work, for the first time, details of the complex formed by heat shock protein 70 (HSP70) independent nucleotide binding domain (NBD) and piperine were characterized through experimental and computational molecular ...
Quantifying transcription factor binding dynamics at the single-molecule level in live cells
(Academic Press Inc Elsevier Science, 2017-07)
Progressive, technological achievements in the quantitative fluorescence microscopy field are allowing researches from many different areas to start unraveling the dynamic intricacies of biological processes inside living ...
Static and dynamic bimolecular fluorescence quenching of porphyrin dendrimers in solution
(SPRINGER/PLENUM PUBLISHERS, 2008)
The fluorescence quenching kinetics of two porphyrin dendrimer series (GnTPPH(2) and GnPZn) by different type of quenchers is reported. The microenvironment surrounding the core in GnPZn was probing by core-quencher ...
Time-resolved fluorescence and anisotropy-sensitive 1,2-dimyristoyl-sn-glycero-3-(7-aminocoumarin) phosphoetanolamide probe for studying membrane lipid domains
(ELSEVIER SCI LTD, 2023)
A fluorescent probe C-DMPE was synthesised to monitor interfacial membrane properties by conjugating coumarin-343 and 1,2-dimyristoyl-sn-glycero-3-phosphorylethanolamine (DMPE), anchoring the 7-aminocou-marin moiety close ...
Fluorescence and molecular dynamics studies of the acetylcholine receptor γM4 transmembrane peptide in reconstituted systems
(Taylor & Francis Ltd, 2009-07-09)
A combination of fluorescence spectroscopy and molecular dynamics (MD) is applied to assess the conformational dynamics of a peptide making up the outermost ring of the nicotinic acetylcholine receptor (AChR) transmembrane ...
Host/guest simulation of fluorescent probes adsorbed into low-density polyethylene, 1 - Excimer formation of 1,3-Di(1-pyrenyl)propane
(Wiley-v C H Verlag GmbhWeinheimAlemanha, 2001)
Insights into interactions of flavanones with target human respiratory syncytial virus M2-1 protein from STD-NMR, fluorescence spectroscopy, and computational simulations
(2020-03-02)
The human Respiratory Syncytial Virus (hRSV) is the most frequent agent of respiratory infections in infants and children with no currently approved vaccine. The M2-1 protein is an important transcriptional antitermination ...
Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer’s Disease
(Humana Press Inc., 2018)