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Força de compressão e umidade no perfil de dissolução da hidroclorotiazida
(2006-01-01)
The aim of this work was to evaluate the influence of compression force and humidity in the dissolution profile of tablets formulation. As hidroclorotyiazide presents real problems of bioavailability, it was incorporate ...
Força de compressão e umidade no perfil de dissolução da hidroclorotiazida
(2006-01-01)
The aim of this work was to evaluate the influence of compression force and humidity in the dissolution profile of tablets formulation. As hidroclorotyiazide presents real problems of bioavailability, it was incorporate ...
Oxfendazole: a promising agent for the treatment and control of helminth infections in humans.
(Taylor and Francis, 2018)
Introduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl] carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite fenbendazole also has anthelminthic action. A very limited ...
Synthesis, cytotoxicity and in vitro antileishmanial activity of naphthothiazoles
(2013-06-01)
The leishmaniasis is a spectral disease caused by the protozoan Leishmania spp., which threatens millions of people worldwide. Current treatments exhibit high toxicity, and there is no vaccine available. The need for new ...
Nanonization techniques to overcome poor water-solubility with drugs
(Universidade Federal de Minas GeraisBrasilFAR - DEPARTAMENTO DE ALIMENTOSUFMG, 2020)
Colloidal carriers for ophthalmic drug delivery
(Bentham Science Publ Ltd, 2014)
Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability
(Future Medicine, 2010-01)
Children constitute the most challenging population in anti-HIV/AIDS pharmacotherapy. Efavirenz (EFV; aqueous solubility 4 µg/ml, bioavailability 40–45%) is a first-line agent in the pediatric therapeutic cocktail. The ...
Co-crystals of non-steroidal anti-inflammatory drugs (NSAIDs): Insight toward formation, methods, and drug enhancement
(2021-10-01)
Pharmaceutical co-crystals have been explored by many researchers as a strategy to optimize physicochemical properties of solid-state drugs. Their improvements of solubility, bioavailability, and the reduced tendency for ...
Development and evaluation of praziquantel solid dispersions in sodium starch glycolate
(2013-04-01)
Purpose: To develop and characterize solid dispersions of praziquantel (PZQ) with sodium starch glycolate (SSG) for enhanced drug solubility. Methods: PZQ solid dispersion (SD) was prepared using co-precipitation method ...
Development and evaluation of praziquantel solid dispersions in sodium starch glycolate
(2013-04-01)
Purpose: To develop and characterize solid dispersions of praziquantel (PZQ) with sodium starch glycolate (SSG) for enhanced drug solubility. Methods: PZQ solid dispersion (SD) was prepared using co-precipitation method ...