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Molecular modeling databases: A new way in the search of protein targets for drug development
(2007-01-01)
DBMODELING is a relational database of annotated comparative protein structure models and their metabolic, pathway characterization. It is focused on enzymes identified in the genomes of Mycobacterium tuberculosis and ...
Molecular modeling databases: A new way in the search of protein targets for drug development
(2007-01-01)
DBMODELING is a relational database of annotated comparative protein structure models and their metabolic, pathway characterization. It is focused on enzymes identified in the genomes of Mycobacterium tuberculosis and ...
Fragment-based QSAR strategies in drug design
(Informa HealthcareLondon, 2010-05)
Recently, fragment-based drug design has been established as a crucial strategy for hit identification and lead generation, which has strongly encouraged the development of approaches to specifically recognize and evaluate ...
Association of Cohort and Individual Substance Use With Risk of Transitioning to Drug Use, Drug Use Disorder, and Remission From Disorder: Findings From the World Mental Health Surveys.
(American Medical Association, 2019)
Importance: Limited empirical research has examined the extent to which cohort-level prevalence of substance use is associated with the onset of drug use and transitioning into greater involvement with drug use. Objective: ...
Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems
(2021-08-01)
Nanotechnology has been widely applied to develop drug delivery systems to improve therapeutic performance. The effectiveness of these systems is intrinsically related to their physicochemical properties, so their biological ...
HCN Channels: New therapeutic targets for pain treatment
(MDPI AG, 2018)
Computer-aided drug design against spike glycoprotein of SARS-CoV-2 to aid COVID-19 treatment
Background: SARS-CoV-2 has the Spike glycoprotein (S) which is crucial in attachment with host receptor and cell
entry leading to COVID-19 infection. The current study was conducted to explore drugs against Receptor ...
An overview of polymeric dosage forms in buccal drug delivery: State of art, design of formulations and their in vivo performance evaluation
(2018-05-01)
Owing to the ease of the administration, the oral cavity is an attractive site for the delivery of drugs. The main difficulty for administration via the buccal route is an effective physiological removal mechanism of the ...