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Characterization of the CYP2D6 drug metabolizing phenotypes of the Chilean mestizo population through polymorphism analyses
(Elsevier, 2015-11)
We tested the influence of four polymorphisms and gene duplication in CYP2D6 on in vivo enzyme activity in a Chilean mestizo population in order to identify the most relevant genetic profiles that account for observed ...
Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease
(NLM (Medline), 2021-03-23)
OBJECTIVE: To investigate the inherent clinical risks associated with the presence of cerebral microhemorrhages (CMHs) or cerebral microbleeds and characterize individuals at high risk for developing hemorrhagic amyloid-related ...
A pílula mágica e o (pré)conceito: a realidade e o impacto da leucemia mielóide crônica na vida do paciente
(Universidade Estadual Paulista (Unesp), 2014-08-14)
The advent of specific drug target for the treatment of Chronic Myeloid Leukemia (CML) in 2001, maybe will score a few more glory days in the history of fighting cancer. These drugs are the result of high medical technology ...
Drogas e criminalidade: avaliação de pacientes portadores de transtorno de personalidade de centros de atenção psicossocial de Aracaju e do hospital de custódia de SergipeDrugs and crime: evaluation of patients with personality disorder of psychosocial care centers in Aracaju and the custody hospital of Sergipe
(DME - Departamento de Medicina – Aracaju - PresencialUniversidade Federal de Sergipe, 2018)
Desenvolvimento e avaliação da liberação in vitro de drug delivery system pH-dependente à base de benznidazol e ZIF-8 visando a obtenção de uma terapia alternativa para a doença de Chagas
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Ciencias Farmaceuticas, 2018)
Novel technologies for the encapsulation of bioactive food compounds
(Elsevier Ltd, 2016-02)
Recent advances in nanoscience and nanotechnologies offer a revolutionary approach to the development of novel and healthier foods. Nano-technological and micro-technological carriers based on biomolecules may be tailored ...
DNA damage in patients infected by Helicobacter pylori
(American Association for Cancer Research (AACR), 2004-04-01)
Helicobacter pylori (H. pylori) is considered to predispose carriers to gastric cancer but its role on gastric carcinogenesis is still unknown. The aim of this study was to investigate DNA damage by the comet assay in ...
DNA damage in patients infected by Helicobacter pylori
(American Association for Cancer Research (AACR), 2004-04-01)
Helicobacter pylori (H. pylori) is considered to predispose carriers to gastric cancer but its role on gastric carcinogenesis is still unknown. The aim of this study was to investigate DNA damage by the comet assay in ...
Effect of DOPA and dopamine coupling on protein loading of hydroxyapatite
(Taylor & Francis Ltd, 2016-01-01)
Hydroxyapatite (HA) is a promising carrier material for oral delivery of biomolecules such as proteins and drugs. Ways to increase the loading of such molecules on HA will lead to better nanomedicine. This study reports ...