Buscar
Mostrando ítems 11-20 de 72
Pros and cons of methylation-based enrichment methods for ancient DNA
(Nature Publishing, 2015)
The recent discovery that DNA methylation survives in fossil material provides an opportunity for novel molecular approaches in palaeogenomics. Here, we apply to ancient DNA extracts the probe-independent Methylated Binding ...
Satellite DNA methylation status and expression of selected genes in Bos indicus blastocysts produced in vivo and in vitro
(2017)
Bovine embryos produced in vivo and in vitro differ with respect to molecular profiles, including epigenetic marks and gene expression profiles. This study investigated the CpG methylation status in bovine testis satellite ...
The reprimo-like gene is an epigenetic-mediated tumor suppressor and a candidate biomarker for the non-invasive detection of gastric cancer
(MDPI, 2020)
Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Here, we evaluated the role of RPRML and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. RPRML ...
Intragenic DNA methylation in buccal epithelial cells and intellectual functioning in a paediatric cohort of males with fragile X
(Nature Publishing Group, 2018)
Increased intragenic DNA methylation of the Fragile X Related Epigenetic Element 2 (FREE2) in blood has been correlated with lower intellectual functioning in females with fragile X syndrome (FXS). This study explored these ...
A DNA-modification methylase from Bacillus stearothermophilus V
(1988)
A type II modification methylase (M BstVI) was partially purified from the thermophilic bacterium Bacillus stearothermophilus V. The methylase catalyses the transfer of methyl groups from S-adenosyl-L-methionine to unmodified ...
DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS
(Taylor & Francis, 2020)
Clinical and experimental evidences indicate that epigenetic modifications induced by the prenatal environment are related to metabolic and reproductive derangements in polycystic ovary syndrome (PCOS). Alterations in the ...
Epigenetic alterations related to early-life stressful events
(Cambridge University Press, 2012)
Objective Early stress events severely impact brain and behaviour. From a neurobiological point of view early stress influences neuroanatomical structures and is associated with a dysregulation of the hypothalamic-pituit ...