Search
Now showing items 31-40 of 721
Use of self-organizing maps and molecular descriptors to predict the cytotoxic activity of sesquiterpene lactones
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2008)
Some sesquiterpene lactones (SLs) are the active compounds of a great number of traditionally medicinal plants from the Asteraceae family and possess considerable cytotoxic activity. Several studies in vitro have shown the ...
Behaviour of N-CH3 Group in Tropane Alkaloids and Correlations in their Properties
(Paripex, 2018-10)
In this work, the influence of common >N-CH3 group present in the three free base, cationic and hydrochloride/bromide structures of scopolamine, heroin, morphine, cocaine and tropane alkaloids in gas and aqueous solution ...
Adaptive matrix metrics for molecular descriptor assessment in QSPR classification
(Chemistry Central, 2010-03)
QSPR methods represent a useful approach in the drug discovery process, since they allow to predict in advance biological or physicochemical properties of a candidate drug. For this goal, it is necessary that the QSPR ...
MolShaCS: a free and open source tool for ligand similarity identification based on Gaussian descriptors
(Elsevier MassonIssy les Moulineaux, 2013-01)
Molecular similarity evaluation is an important step in most drug development strategies, since molecular similarity is usually related to functional similarity. Here, we developed a method based on the Gaussian description ...
Multiscale Fractal Descriptors and Polynomial Classifier for Partial Pixels Identification in Regions of Interest of Mammographic Images
(Institute of Electrical and Electronics Engineers (IEEE), 2012-06-01)
Computer systems are used to support breast cancer diagnosis, with decisions taken from measurements carried out in regions of interest (ROIs). We show that support decisions obtained from square or rectangular ROIs can ...
Multiscale Fractal Descriptors and Polynomial Classifier for Partial Pixels Identification in Regions of Interest of Mammographic Images
(Institute of Electrical and Electronics Engineers (IEEE), 2012-06-01)
Computer systems are used to support breast cancer diagnosis, with decisions taken from measurements carried out in regions of interest (ROIs). We show that support decisions obtained from square or rectangular ROIs can ...
Solving analytical structured formalisms in parallel using slice algorithm
(Universidad de Los Andes, 2009)
Multiscale Fractal Descriptors and Polynomial Classifier for Partial Pixels Identification in Regions of Interest of Mammographic Images
(Institute of Electrical and Electronics Engineers (IEEE), 2014)