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Understanding the Role of the DEAD-Box Helicase DDX3 in Viral and Cellular Messenger RNA Metabolism
(2015)
DEAD-box polypeptide 3, o DDX3, pertenece a la familia de las proteínas DEAD-box, las cuales corresponden a helicasas de ARN dependientes de ATP. DDX3 ha sido involucrada en diferentes procesos del metabolismo de ARN desde ...
Quantification of DDX3Y, RBMY1, DAZ and TSPY mRNAs in testes of patients with severe impairment of spermatogenesis
(2007)
Y chromosome microdeletion is the most important genetic cause of impairment of spermatogenesis. Nevertheless, a significant proportion of patients with spermatogenic failure do not have this condition. This study investigated ...
The role of the dead-box rna helicase ddx3 in mrna metabolism
(WILEY-BLACKWELL, 2013)
The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA
(Oxford University Press, 2013)
Here, we show a novel molecular mechanism
promoted by the DEAD-box RNA helicase DDX3 for
translation of the HIV-1 genomic RNA. This occurs
through the adenosine triphosphate-dependent formation
of a translation initiation ...