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Ketamine Increases the Function of γ-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons
(Lippincott Williams and Wilkins, 2017)
© 2016, the American Society of Anesthesiologists, Inc. Wolters Kluwer Health, Inc. All Rights Reserved.Background: The dissociative general anesthetic ketamine is a well-known N-methyl-d-aspartate receptor antagonist. ...
Oleoylethanolamide and Palmitoylethanolamide Protect Cultured Cortical Neurons Against Hypoxia
(Mary Ann Liebert, 2018-09)
Introduction: Perinatal hypoxic-ischemic (HI) encephalopathy is defined as a neurological syndrome where the newborn suffers from acute ischemia and hypoxia during the perinatal period. New therapies are needed. The ...
Docosahexaenoic acid (dha)-induced neuroprotectión in cortical neurons involves ppar gamma activatión and dha-mediated synthesis of 18-hydroxy eicosapentaenoic acid
(2013)
Peroxisome proliferator-activated receptor gamma (PPAR?) is a nuclear receptor that controls the expression of several genes involved in lipid homeostasis, inflammation, cancer and diabetes. PPAR? is activated by synthetic ...
Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: Implications for protection of striatal neurons expressing mutant huntingtin
(BioMed Central, 2020-10)
Background: Evidence shows significant heterogeneity in astrocyte gene expression and function. We previously demonstrated that brain-derived neurotrophic factor (BDNF) exerts protective effects on whole brain primary ...
GABA released from cultured cortical neurons influences the modulation of t-[35S]butylbicyclophosphorothionate binding at the GABAA receptor: Effects of thymol
(Elsevier Science, 2008-12)
Thymol is a monoterpene that specifically interacts with synaptic neural functions in neuronal GABA-operated Cl- channels. Here we explore the effects of thymol, and propofol as positive control, on t-[35S]butylbicycloph ...
Specification of excitatory neurons in the developing cerebral cortex: progenitor diversity and environmental influences
(2015-01-12)
The mature cerebral cortex harbors a heterogeneous population of glutamatergic neurons,
organized into a highly intricate histological architecture. Classically, this mixed population
of neurons was thought to be generated ...
The neuronal GABAA receptor as target for therapeutic and toxic chemical compounds: In vitro studies using cultured cortical neurons
(Asociación de Químicos e Ingenieros, 2007-12)
Los neurotransmisores son sustancias químicas liberadas por las neuronas y reconocidas por proteínas o receptores específicos situados en la membrana celular. El control de la neurotransmisión excitadora e inhibidora es ...
Inhibition of cPLA(2) and sPLA(2) Activities in Primary Cultures of Rat Cortical Neurons by Centella asiatica Water Extract
(NATURAL PRODUCTS INCWESTERVILLE, 2012)
Leaf extract of Centella asiatica has been used as an alternative medicine for memory improvement in the Indian Ayurvedic system of medicine for a long time. Although several studies have revealed its effect in ameliorating ...
Kinesin KIF4A transports integrin β1 in developing axons of cortical neurons
(Academic Press Inc Elsevier Science, 2014-09)
CNS axons have poor regenerative ability compared to PNS axons, and mature axons regenerate less well than immature embryonic axons. The loss of regenerative ability with maturity is accompanied by the setting up of a ...