Now showing items 1-10 of 166
GDNF/GFRα1 Complex Abrogates Self-Renewing Activity of Cortical Neural Precursors Inducing Their Differentiation
(Cell Press, 2018-03)
The balance between factors leading to proliferation and differentiation of cortical neural precursors (CNPs) determines the correct cortical development. In this work, we show that GDNF and its receptor GFRα1 are expressed ...
Protocol for evaluating neuronal polarity in murine models
(Cell Press, 2020-12)
The establishment of polarity is crucial for the physiology and wiring of neurons. Therefore, monitoring the axo-dendritic specification allows the mechanisms and signals associated with development, growth, and disease ...
Antioxidant responses of cortex neurons to iron loading
(Sociedad de Biología de Chile, 2006)
Allosteric positive interaction of thymol with the GABA-A receptor in primary cultures of mouse cortical neurons
(Pergamon-Elsevier Science Ltd, 2006-01)
Thymol is a naturally occurring phenolic monoterpene known for its anti-microbial and anti-oxidant properties. It is used in dental practice and in anaesthetic halothane preparations. Recent studies have reported enhanced ...
Quantitative Analysis Of Rat Dorsal Root Ganglion Neurons Cultured On Microelectrode Arrays Based On Fluorescence Microscopy Image Processing
(WORLD SCIENTIFIC PUBL CO PTE LTDSINGAPORE, 2015)
S-nitrosylation of proteins in hippocampal and cortical neurons in excitotoxicity: differential regulation of NF-kB
Cell death by excitotoxicity is a consequence of excessive stimulation of N-methyl-Daspartate (NMDA) receptors, causing calcium overload and synthesis of nitric oxide. Hippocampal neurons are selectively sensitive to ...
p75 NTR expression is induced in isolated neurons of the penumbra after ischemia by cortical devascularization
(Wiley-liss, div John Wiley & Sons Inc., 2009-10)
The p75 neurotrophin receptor (p75NTR) is involved in neuronal functions going from induction of apoptosis and growth inhibition to the promotion of survival. p75NTR expression is induced in central nervous system (CNS) ...
The role of zinc in the modulation of neuronal proliferation and apoptosis
Although a requirement of zinc (Zn) for normal brain development is well documented, the extent to which Zn can modulate neuronal proliferation and apoptosis is not clear. Thus, we investigated the role of Zn in the ...
Neurotransmitter amines and antioxidant agents in neuronal protection against methylmercury-induced cytotoxicity in primary cultures of mice cortical neurons
(Elsevier Science, 2018-12)
Methylmercury (MeHg) is an environmental toxicant with detrimental effects on the developing brain and adult nervous system. The main mechanisms identified include oxidative stress, changes in intracellular calcium, ...