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Application of copper(I)-catalysed azide/alkyne cycloaddition (CuAAC) `click chemistry` in carbohydrate drug and neoglycopolymer synthesis
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
A peptide-based coating toolbox to enable click chemistry on polymers, metals, and silicon through sortagging
(Wiley-Blackwell, 2021-02-04)
A versatile peptide-based toolbox for surface functionalization was established by a combination of a universal material binding peptide (LCI-anchor peptide) and sortase-mediated bioconjugation (sortagging). This toolbox ...
Preparation of bifunctional mesoporous silica nanoparticles by orthogonal click reactions and their application in cooperative catalysis
(Wiley-VCH VerlagWeinheim, 2012-12)
The synthesis of bifunctional mesoporous silica nanoparticles is described. Two chemically orthogonal functionalities are incorporated into mesoporous silica by co-condensation of tetraethoxysilane with two orthogonally ...
Synthesis, antiviral and cytotoxic activity of novel terpenyl hybrid molecules prepared by click chemistry
(Molecular Diversity Preservation International, 2018-06)
Naturally occurring terpenes were combined by click reactions to generate sixteen hybrid molecules. The diterpene imbricatolic acid (IA) containing an azide group was used as starting compound for the synthesis of all the ...
Química bioortogonal: cuando los organismos vivos se convierten en matraces de reacción
(Pontificia Universidad Católica del Perú, 2023)
Green by Design: Convergent Synthesis, Computational Analyses, and Activity Evaluation of New FXa Inhibitors Bearing Peptide Triazole Linking Units
(2022)
Green chemistry implementation has led to promising results in waste reduction in the pharmaceutical industry. However, the early sustainable development of pharmaceutically active compounds and ingredients remains a ...
Palladium Nanoparticles Embedded in a Layer-by-Layer Nanoreactor Built with Poly(Acrylic Acid) Using "electro-Click Chemistry"
(American Chemical Society, 2016-07)
Palladium nanoparticles (Pd NPs) were formed by electrochemical reduction of Pd(NH3)43+ ions entrapped by ion exchange in poly(acrylic acid) (PAA) multilayer films grown by the Sharpless "click reaction." The alkyne (PAAalk) ...
Simple thiol-ene click chemistry modification of SBA-15 silica pores with carboxylic acids
(Academic Press Inc Elsevier Science, 2015-07)
A straightforward approach for anchoring tailored carboxylic groups in mesoporous SiO2 colloidal materials is presented. The thiol-ene photochemical reaction between vinyltrimethoxysilane precursors and various thiocarboxylic ...
Multicomponent click synthesis of potentially biologically active triazoles catalysed by copper nanoparticles on activated carbon in water
(Pergamon-Elsevier Science Ltd, 2012-01)
A variety of potentially biologically active 1,2,3-triazoles, derived from (-)-menthol, lactic acid, D-glucose, oestrone, cholesterol, and phenacetin, have been synthesised through the multicomponent alkyne-azide 1,3-dipolar ...
Síntese de novos derivados triazólicos e avaliação de suas atividades antifúngicas
(Universidade Federal de Minas GeraisBrasilICX - DEPARTAMENTO DE QUÍMICAPrograma de Pós-Graduação em QuímicaUFMG, 2019-08-20)
In the last three decades, the mortality rate caused by fungal infections has substantially increased due the appearance of new pathogenic fungi and the emergence of infections resistant to the available drugs for treatment. ...