Now showing items 21-30 of 724
Enantioselective analysis of oxybutynin and N-desethyloxybutynin with application to an in vitro biotransformation study
(ELSEVIER SCIENCE BV, 2008)
An enantioselective method using liquid-phase microextraction (LPME) followed by HPLC analysis was developed for the determination of oxybutynin (OXY) and its major metabolite N-desethyloxybutynin (DEO) in rat liver ...
Chiral HPLC analysis of venlafaxine metabolites in rat liver microsomal preparations after LPME extraction and application to an in vitro biotransformation study
(SPRINGER HEIDELBERG, 2010)
A three-phase LPME (liquid-phase microextraction) method for the enantioselective analysis of venlafaxine (VF) metabolites (O-desmethylvenlafaxine (ODV) and N-desmethylvenlafaxine (NDV) in microsomal preparations is described ...
Evaluation of Diuron Tolerance and Biotransformation by Fungi from a Sugar Cane Plantation Sandy-Loam Soil
(Amer Chemical Soc, 2016-12-14)
Microorganisms capable of degrading herbicides are essential to minimize the amount of chemical compounds that may leach into other environments. This work aimed to study the potential of sandy-loam soil fungi to tolerate ...
Citotoxicity of Fipronil on Hepatocytes Isolated from Rat and Effects of Its Biotransformation
(Inst Tecnologia Parana, 2015-11-01)
The aim of this study was to characterize the mechanism of toxicity of fipronil on hepatocytes isolated from the rat and the effect of its biotransformation on the toxicological potential. The toxicity of fipronil was ...
Biotransformation of labdane and halimane diterpenoids by two filamentous fungi strains
Biotransformation of natural products by filamentous fungi is a powerful and effective approach to achieve derivatives with valuable new chemical and biological properties. Although diterpenoid substrates usually exhibit ...
Biotransformation of halogenated 2′-deoxyribosides by immobilized lactic acid bacteria
(Elsevier Science, 2012-04-11)
An efficient and green bioprocess is herein reported to obtain halogenated nucleosides by transglycosylation using immobilized lactic acid bacteria (LAB). Lactobacillus animalis ATCC 35046 showed a yield of 95% at 0.5 h ...
Modificação de óleos e gorduras por biotransformaçãoModification of oils and fats by biotransformation
(Sociedade Brasileira de Química, 2004)