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Completely uniformly distributed sequences based on de Bruijn sequences
(American Mathematical Society, 2020-04)
We study a construction published by Donald Knuth in 1965 yielding a completely uniformly distributed sequence of real numbers. Knuth's work is based on de Bruijn sequences of increasing orders and alphabet sizes, which ...
Controlling for contamination in re-sequencing studies with a reproducible web-based phylogenetic approach
(2014)
Polymorphism discovery is a routine application of next-generation sequencing technology where multiple samples are sent to a service provider for library preparation, subsequent sequencing, and bioinformatic analyses. The ...
Sequencing human rhinoviruses: Direct sequencing versus plasmid cloning
(Elsevier Science, 2015-01)
Human rhinoviruses (RV) are associated with the majority of viral respiratory illnesses in infants, children and adults. Over the last several years, researchers have begun to sequence the many different species and strains ...
A Hybrid Approach using Progressive and Genetic Algorithms for Improvements in Multiple Sequence Alignments
(Scitepress, 2021-01-01)
The multiple sequence alignment is one of the main tasks in bioinformatics. It is used in different important biological analysis, such as function and structure prediction of unknown proteins. There are several approaches ...