Buscar
Mostrando ítems 2041-2050 de 4982
Immune response modulation by vitamin D: role in systemic lupus erythematosus
(2015)
Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of ...
Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features
(2016)
Tolerogenic dendritic cells (TolDCs) are promising tools for therapy of autoimmune diseases, such as rheumatoid arthritis (RA). Here, we characterize monocyte-derived TolDCs from RA patients modulated with dexamethasone ...
Dexamethasone and monophosphoryl lipid a-modulated dendritic cells promote antigen-specific tolerogenic properties on naive and memory cd4+ t cells.
(2016)
Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs ...
Skewing dendritic cell differentiation towards a tolerogenic state for recovery of tolerance in rheumatoid arthritis.
(2015)
To date, the available options to treat autoimmune diseases such as rheumatoid arthritis (RA) include traditional corticoids and biological drugs, which are not exempt of adverse effects. The development of cellular therapies ...
Dendritic cells from rheumatoid arthritis patients conditioned with dexamethasone and activated with monophosphoryl lipid-A, exhibit strong migratory capacity and impaired T cell responses to synovial
(2014)
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized
by synovial joints inflammation, cartilage breakdown and bone destruction. Dendritic cells
(DCs) are central on RA pathogenesis due to ...
Dexamethasone-modulated dendritic cells from rheumatoid arthritis patients activated with monophosphoryl lipid-A, display migratory capacity and induce reduced T cell responses to synovial antigens
(2014)
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized
by synovial joints inflammation, cartilage breakdown and bone destruction. Dendritic cells
(DCs) are central on RA pathogenesis due to ...
Treatment with dexamethasone and monophosphoryl lipid A removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the abi
(2016)
Background/Purpose: Tolerogenic dendritic cells (TolDCs) are promising tools for therapy of autoimmune diseases such
as rheumatoid arthritis (RA). Here we characterise TolDCs from RA patients modulated with dexamethasone ...
Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients and healthy controls induces a transcriptional modulation of genes related to cell recruitment,
(2016)
Background: Despite growing interest in tolerogenic dendritic
cells (tolDCs) as target for immunotherapy in autoimmunity, the
molecular mechanisms driving differentiation of tolDCs towards
a regulatory phenotype are poorly ...
Informe Final Centro (CRCP) 2000-2009
(2000)
The FONDAP Center for Cell Regulation and Pathology “Joaquin V. Luco” has as main purposes to stimulate research activity and scientific training in basic areas of modern Biomedical Sciences. The Center is inserted on the ...
FOCIS goes south: advances in translational and clinical immunology
(2017)
FOCIS goes South: Advances in Translational and Clinical Immunology was the first Federation of Clinical Immunology Societies (FOCIS) (www. focisnet. org) meeting held in Latin America (May 15-17, 2017, Santiago de Chile, ...