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Position statement of the Brazilian Academy of Rhinology on the use of antihistamines, antileukotrienes, and oral corticosteroids in the treatment of inflammatory sinonasal diseases
(Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2017)
Introduction: Inflammatory conditions of the nose and paranasal sinuses are very prevalent in the general population, resulting in marked loss of quality of life in affected patients, as well as significant work, leisure, ...
USING OF FIRST GENERATION OF Hl ANTIHISTAMINES As ALTERNATIVE OF LOCAL ANESTHETIC IN ODONTOLOGIC USE IN ANESTHESIA INFILTRATIVE TECHNICS. EXPERIMENTAL STUDY IN ANIMALSEMPLEO DE ANTIHISTAMÍNICOS H1 DE PRIMERA GENERACIÓN COMO ALTERNATIVA A LOS ANESTÉSICOS LOCALES DE USO ODONTOLÓGICO EN TÉCNICAS DE ANESTESIA INFILTRATIVA. ESTUDIO EXPERIMENTAL EN ANIMALES
(Universidad Nacional Mayor de San Marcos, Facultad de Odontología, 2004)
Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways
(Nature Publishing Group, 2015-12)
Histamine H1 receptor (H1R) antagonists and glucocorticoid receptor (GR) agonists are used to treat inflammatory conditions such as allergic rhinitis, atopic dermatitis and asthma. Consistent with the high morbidity levels ...
Potential negative effects of anti-histamines on male reproductive function
(BioScientifica, 2018-04)
Histamine (HA) is a pleiotropic biogenic amine synthesized exclusively by histidine decarboxylase (HDC) in most mammalian tissues. The literature on the role of HA within the male gonad has expanded over the last years, ...
Histamine H-4 Receptor Ligands: Future Applications and State of Art
(Wiley-Blackwell, 2015-04-01)
Histamine is a chemical transmitter found practically in whole organism and exerts its effects through the interaction with H-1 to H-4 histaminergic receptors. Specifically, H-4 receptors are found mainly in immune cells ...
Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents
(2006)
The chemical structure of phenothiazine provides a most valuable molecular template for the development of agents able to interact with a wide variety of biological processes. Synthetic phenothiazines (with aliphatic, ...
Estudo termoanalítico e caracterização no estado sólido de alguns anti-histamínicos
(Universidade Estadual Paulista (UNESP), 2014)