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Regulatory T cell expansion resolves after effective strongyloidiasis treatment in subjects with HTLV-1 co-infection
(Elsevier, 2020)
BACKGROUND: Regulatory T-cells (Tregs) are increased in patients with HTLV-1/Strongyloides stercoralis co-infection, and they may modify otherwise protective antigen-specific cytokine production. We hypothesized that ...
Regulation of T cell response to leishmania antigens by determinants of histocompatibility leukocyte class I and II molecules
(Brazilian Journal of Medical and Biological Research, 1998)
It has been shown that HLA class I molecules play a significant role in the regulation of the proliferation of T cells activated by mitogens and antigens. We evaluated the ability of mAb to a framework determinant of HLA ...
Proliferating cell nuclear antigen immunoreaction in adrenal-tumors
(Casa Editrice Ambrosiana, 1995-07-01)
Aims mid background: We studied, retrospectively, 33 cases of adrenal tumors of children at the Pediatric Endocrinology Unit, Children's Institute, Sao Paulo State University Medical School, from 1975 to 1993. Ail patients ...
Editorial: T-Cell Migration in Health and Disease
(Frontiers Media, 2017)
HLA-DR marks recently divided antigen-specific effector CD4 T cells in active tuberculosis patients
(American Association of Immunologists, 2021)
Upon Ag encounter, T cells can rapidly divide and form an effector population, which plays an important role in fighting acute infections. In humans, little is known about the molecular markers that distinguish such effector ...
Dexamethasone-treated and monophosphoryl lipid a-activated dendritic cells induce antigen-specific naive CD4+ T cells hyporesponsiveness
(2014)
Introduction: Dendritic cells (DCs) are antigen-presenting cells that initiate and modulate
adaptive immune responses, inducing either immunity or tolerance. In vitro generated DCs
with tolerogenic properties are promising ...
Antigen discovery for the identification of vaccine candidates and biomarkers using a T cell driven approach in combination with positional scanning peptide libraries
(Elsevier, 2015-03)
The prevention and treatment of infectious diseases is highly dependent on the availability of reliable diagnostic tests and protective or therapeutic vaccines. There also exists an urgent need to develop reliable biomarkers ...
T cell receptor binding kinetics required for t cell activation depend on the density of cognate ligand on the antigen-presenting cell
(NATIONAL ACADEMY OF SCIENCES, 2005)