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The essential role of annexin A1 mimetic peptide in the skin allograft survival
(2013)
Immunosuppressive drugs have a critical role in inhibiting tissue damage and allograft rejection.Studies have demonstrated the anti-infl ammatory effects of the annexin A1 (AnxA1) in the regulationof transmigration and ...
Expression of annexin A1 in Leishmania-infected skin and its correlation with histopathological features
(Sociedade Brasileira de Medicina Tropical, 2015)
Interaction of the Anti-Inflammatory Annexin A1 Protein and Tacrolimus Immunosuppressant in the Renal Function of Rats
(Karger, 2010-01-01)
Background: Tacrolimus (FK) is currently widely used in transplant immunosuppression and the treatment of autoimmune diseases. However, FK induces nephrotoxicity which is characterized by functional and structural renal ...
Mimetic peptide AC2-26 of annexin A1 as a potential therapeutic agent to treat COPD
(2018-10-01)
Chronic obstructive pulmonary disease (COPD) is related to inflammatory process caused by smoking habit. In this scenario, the anti-inflammatory protein Annexin A1 (AnxA1) may represent a therapeutic alternative. We performed ...
Annexin A1 protein attenuates cyclosporine-induced renal hemodynamics changes and macrophage infiltration in rats
(Springer Basel Ag, 2012-03-01)
Cyclosporine (CsA) remains an important immunosuppressant for transplantation and for treatment of autoimmune diseases. The most troublesome side effect of CsA is renal injury. Acute CsA-induced nephrotoxicity is characterized ...
Expression of the Annexin A1 and its correlation with matrix metalloproteinases and the receptor for formylated peptide-2 in diffuse astrocytic tumors
(2018-12-01)
Astrocytomas represent the majority of cerebral gliomas. Studies show that the anti-inflammatory protein Annexin-A1 (ANXA1) is associated with the tumor invasion process and that its actions can be mediated by the receptor ...
Interaction of the Anti-Inflammatory Annexin A1 Protein and Tacrolimus Immunosuppressant in the Renal Function of Rats
(Karger, 2010-01-01)
Background: Tacrolimus (FK) is currently widely used in transplant immunosuppression and the treatment of autoimmune diseases. However, FK induces nephrotoxicity which is characterized by functional and structural renal ...
Effect of annexin-A1 peptide treatment during lung inflammation induced by lipopolysaccharide
(Academic Press Ltd Elsevier B.V. Ltd, 2012-08-01)
Lung endotoxemia is characterized by neutrophil accumulation, increased vascular permeability and parenchymal injury. This can also affect the endogenous pathways that operate in the host to keep inflammation under control. ...
Effect of annexin-A1 peptide treatment during lung inflammation induced by lipopolysaccharide
(Academic Press Ltd Elsevier B.V. Ltd, 2012-08-01)
Lung endotoxemia is characterized by neutrophil accumulation, increased vascular permeability and parenchymal injury. This can also affect the endogenous pathways that operate in the host to keep inflammation under control. ...