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Now showing items 31-40 of 99
Neosaxitoxin as a local anesthetic: Preliminary observations from a first human trial
(2007)
BACKGROUND: Neosaxitoxin is a phycotoxin that reversibly blocks the voltage-gated sodium channels at the neuronal level. Its activity results in blocking the axonal conduction, stopping the propagation of the nerve impulse. ...
Comparison of neosaxitoxin versus bupivacaine via port infiltration for postoperative analgesia following laparoscopic cholecystectomy: A randomized, double-blind trial
(2011)
Background and Objectives: Wound infiltration with available local anesthetics generally provides analgesia for less than 8 hrs. The site 1 sodium-channel toxin neosaxitoxin (neoSTX) produced analgesia for over 24 hrs in ...
A multicenter, randomized comparison between 2, 5, and 8 mg of perineural dexamethasone for ultrasound-guided infraclavicular block
(BMJ Publishing Group, 2019)
© 2019 American Society of Regional Anesthesia & Pain Medicine.Background and objectives This multicenter, randomized trial compared 2, 5, and 8 mg of perineural dexamethasone for ultrasound-guided infraclavicular brachial ...
Treatment of complex regional pain syndrome: an updated systematic review and narrative synthesis Traitement du syndrome douloureux régional complexe : étude systématique actualisée et synthèse narrative
(Springer New York LLC, 2018)
© 2018, Canadian Anesthesiologists' Society. Purpose: Although multiple treatments have been advocated for complex regional pain syndrome (CRPS), the levels of supportive evidence are variable and sometimes limited. The ...
A Randomized Comparison between Interscalene and Small-Volume Supraclavicular Blocks for Arthroscopic Shoulder Surgery
(Lippincott Williams and Wilkins, 2018)
© 2018 by American Society of Regional Anesthesia and Pain Medicine. Background and Objectives This randomized trial compared ultrasound (US)-guided interscalene block (ISB) and small-volume supraclavicular block (SCB) for ...
Respiratory, neuromuscular, and cardiovascular effects of neosaxitoxin in isoflurane-anesthetized sheep
(2012)
Background: Neosaxitoxin (NeoSTX) is a potent site-1 sodium-channel blocker being developed as a local anesthetic. Doses of 100 μg have been used by local infiltration in anesthetized adult humans without adverse effect. ...
Geographical distribution of acute lymphoblastic leukaemia subtypes: Second report of the collaborative group study
(Nature Publishing Group, 1993)
Childhood acute lymphoblastic leukaemia (ALL) T and B precursor subtypes have been identified by standardised immunophenotyping in different geographic and ethnic settings. Comparison of the relative frequencies and estimated ...
The effect of nitrous oxide on jugular bulb oxygen saturation during remifentanil plus target-controlled infusion propofol or sevoflurane in patients with brain tumors
(2002)
During propofol/fentanyl anesthesia, a large percentage of patients have jugular bulb oxygen saturation (Sjo2) <50%. The incidence is less with isoflurane/N2O. We evaluated the effect of N2O on Sjo2 during remifentanil-based ...
A basic anesthesia training program for nurses in Chad: first steps for a south–south academic cooperation program Programme de formation de base en anesthésie pour le personnel infirmier au Tchad: premiers pas d’un programme de coopération académique sud
(Springer New York LLC, 2019)
Purpose: Safe perioperative care remains a large public healthcare problem in low- and middle-income countries. Anesthesia care provided by trained professionals is one of the essential determinants to address this situation. ...
Diaphragm-sparing nerve blocks for shoulder surgery, revisited
(BMJ PUBLISHING GROUP, 2020)
Although interscalene brachial plexus block (ISB) remains the gold standard for analgesia after shoulder surgery, the inherent risks of ipsilateral phrenic nerve block and hemidiaphragmatic paralysis (HDP) limit its use ...