Objective: Although the efficacy of systemic corticosteroids (SCs) in acute asthma exacerbations is well established, the fact that many children still require admission to hospital and that SCs have a slow onset of action ...

Progressive lung function decline and, ultimately, respiratory failure are the most common cause of death in patients with cystic fibrosis (CF). This decline is punctuated by acute pulmonary exacerbations (APEs), and in ...

This study was undertaken to investigate the mechanisms that determine abnormal gas exchange during acute exacerbations of chronic obstructive pulmonary disease (COPD). Thirteen COPD patients, hospitalized because of an ...

Introduction: In moderate-severe asthma exacerbation, salbutamol by inhaler (MDI) issuperior to salbutamol delivered by nebulizer (NEB); however, to our knowledge, nostudies in children with exclusively severe exacerbations ...

The most common cause of death in cystic fibrosis (CF) patients is progressive lung function decline, which is punctuated by acute pulmonary exacerbations (APEs). A major challenge is to discover biomarkers for detecting ...

Respiratory tract infections have an important clinical and economic impact and they are the most common indication for antibiotic use in outpatient practice. This prospective, multicenter non-controlled trial assessed the ...

Interstitial lung disease (ILD) is a heterogeneous group of disorders characterized by dyspnea and bilateral infiltrations of the lung. While some cases are idiopathic (e.g., idiopathic pulmonary fibrosis), others are ...

Background: Acute exacerbation of COPD negatively affects the disease, impairs lung function, functional capacity and health status and increases the risk for the development of cardiovascular diseases (CVD), and the ...