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Acute promyelocytic leukemia: the study of t(15;17) translocation by fluorescent in situ hybridization, reverse transcriptase-polymerase chain reaction and cytogenetic techniques
(Associação Brasileira de Divulgação Científica, 2001-06-01)
Acute promyelocytic leukemia (AML M3) is a well-defined subtype of leukemia with specific and peculiar characteristics. Immediate identification of t(15;17) or the PML/RARA gene rearrangement is fundamental for treatment. ...
Apoptosis induction by (+)alpha-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
We analyzed the effect of (+)alpha-tocopheryl succinate (alpha-TOS) alone or associated with arsenic trioxide (ATO) or all-trans retinoid acid (ATRA) in acute promyelocytic leukemia (APL). alpha-TOS-induced apoptosis in ...
Leucemia promielocítica aguda: do histórico ao tratamentoAcute promyelocytic leukemia: from history to treatment
(Universidade Federal do Rio Grande do NorteBrasilUFRNBiomedicinaCentro de Biociências, 2022)
Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia
(AMER SOC HEMATOLOGY, 2009)
Acute promyelocytic leukemia (APL) is characterized by a block in differentiation and accumulation of promyelocytes in the bone marrow and blood. The majority of APL patients harbor the t(15: 17) translocation leading to ...
Cardiac stunning as a manifestation of ATRA differentiation syndrome in acute promyelocytic leukemia
(HUMANA PRESS INCTOTOWA, 2012)
Noma-like lesion in a patient with acute promyelocytic leukemia
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2011)
Apoptotic Effects Of Green Tea In Leukemic Cells From Acute Promyelocytic Leukemia Mice
(Amer Soc Cell BiologyBethesda, 2016)
Subtipos moleculares de PML/RARα en pacientes con leucemia promielocítica aguda
(Instituto Nacional de Salud, 2013)
The Objetive: was to describe the frequency of molecular subtypes of PML/RARα in patients with acute promyelocytic leukemia (APL) and their distribution according to risk of recurrence and cytomorphology. A case series was ...
Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines
(Ferrata Storti Foundation, 2007-10-01)
We report an increased incidence of high relapse risk features in 157 APL Brazilian patients. Out of 134 patients treated with ATRA and anthracyclines, only 91 (67.9%) achieved remission because 43 (32%) died during ...