Synaptic receptors gate the neuronal response to incoming signals, but they are not homogeneously distributed on dendrites. A spatially defined receptor distribution can preferentially amplify certain synaptic inputs, ...

The neurobiology of memory formation attracts much attention in the last five decades. Conversely, the rules that govern and the mechanisms underlying forgetting are less understood. In addition to retroactive interference, ...

Loss of vision in glaucoma results from the selective death of retinal ganglion cells (RGCs). Tumor necrosis factorα (TNFα) signaling has been linked to RGC damage, however, the mechanism by which TNFα promotes neuronal ...

Microinjection of S-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid ( AMPA) in the nucleus of the solitary tract (NTS) of conscious rats causes hypertension, bradycardia, and vasoconstriction in the renal, mesenteric, ...

Estudos prévios clínicos e pré-clínicos sugerem o envolvimento do córtex orbitofrontal (COF) e da neurotransmissão glutamatérgica no transtorno obsessivo-compulsivo (TOC). A ketamina, um antagonista não competitivo dos ...

Estudos prévios clínicos e pré-clínicos sugerem o envolvimento do córtex orbitofrontal (COF) e da neurotransmissão glutamatérgica no transtorno obsessivo-compulsivo (TOC). A ketamina, um antagonista dos receptores ...

The aim of this study was to analyze the plastic effects of moderate exercise upon the motor cortex (M1 and M2 areas), cerebellum (Cb), and striatum (CPu) of the rat brain This assessment was made by verifying the expression ...