Now showing items 1-8 of 8
What are the comparative effects of ethosuximide, sodium valproate, or lamotrigine for children and adolescents with absence seizures?
(Cochrane Clinical Answers, 2019-10-07)
For children and adolescents with absence seizures, there was little or no evidence of a difference in outcomes between ethosuximide and valproate. However, lamotrigine was less effective than other treatments; fewer ...
How does levetiracetam compare with other anti-epileptic drugs in terms of congenital malformations in children?
Reviewers assessed the incidence of congenital malformations in children associated with levetiracetam versus carbamazepine, gabapentin, lamotrigine, oxycarbazepine, phenobarbital, phenytoin, topiramate, zonisamide, and ...
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry
(Elsevier Science Inc, 2018-06)
Background: Evidence for the comparative teratogenic risk of antiepileptic drugs is insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the occurrence of major congenital malformations ...
Treating alcohol use disorder in U.S. veterans: The role of traumatic brain injury
(American Neuropsychiatric Association, 2019-10)
Objective: The authors examined the efficacy of valproate to reduce relapse to heavy drinking among veterans with alcohol use disorder (AUD) and neuropsychiatric comorbidities and whether antecedent traumatic brain injury ...
How does lithium compare with mood stabilizers for people with acute mania?
For adults with acute mania, the effects of lithium compared with different mood stabilizers were mixed, and although differences were noted, few reached statistical significance. The comparative adverse effect pattern ...