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Exploring the toxicity, lung distribution, and cellular uptake of rifampicin and ascorbic acid-loaded alginate nanoparticles as therapeutic treatment of lung intracellular infections
(American Chemical Society, 2020-12)
Nanotechnology is a very promising technological tool to combat health problems associated with the loss of effectiveness of currently used antibiotics. Previously, we developed a formulation consisting of a chitosan and ...
Assessment of Plasma Zinc and Total Leukocyte Count in Calves Experimentally Infected with Mannheimia haemolytica
(Springer, 2020-04-19)
Mannheimia haemolytica is the main bacterial pathogen isolated in bovine respiratory disease (BRD), a common disease affecting calves before weaning. Previous research has shown that experimental infection with bovine ...
Nasal Priming with Lactobacillus rhamnosus CRL1505 Stimulates Mononuclear Phagocytes of Immunocompromised Malnourished Mice: Improvement of Respiratory Immune Response
(Springer New York LLC, 2019-05)
The effect of Lactobacillus rhamnosus CRL1505 (Lr) on macrophages (Ma) and dendritic cells (DC) in the orchestration of anti-pneumococcal immunity was studied using malnutrition and pneumococcal infection mouse models. ...
Chicken egg yolk antibodies against bovine respiratory syncytial virus neutralize the virus in vitro
(Elsevier, 2012)
Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive ...
New proposal involving nanoformulated melatonin targeted to the mitochondria as a potential COVID-19 treatment
(Future Medicine, 2020-12)
Melatonin may be a powerful auxiliary therapy in the prevention and treatment of viral infections, such as coronavirus disease 2019 (COVID-19). Casually, the so-called ‘super immunity’ of bats and the usually high levels ...
Prevention and Treatment of Acute Respiratory Distress Syndrome by COVID-19: Role of Vitamin D on Immunomodulation and Renin-Angiotensin-Aldosterone System Regulation
(Biomedical Research Network, 2021-10)
The leading cause of complications or death from COVID-19 is due to the development of acute respiratory distress syndrome (ARDS). This syndrome is characterized by exacerbated inflammation, mainly at the pulmonary level, ...
Immunobiotic lactobacilli improve resistance of respiratory epithelial cells to sars-cov-2 infection
(Molecular Diversity Preservation International, 2021-09)
Previously, we reported that immunomodulatory lactobacilli, nasally administered, benefi-cially regulated the lung antiviral innate immune response induced by Toll-like receptor 3 (TLR3) activation and improved protection ...
Orally administered Lactobacillus rhamnosus modulates the respiratory immune response triggered by the viral pathogen-associated molecular pattern poly(I:C)
(Biomed Central, 2012-09)
Some studies have shown that probiotics, including Lactobacillus rhamnosus CRL1505, had the potential to beneficially modulate the outcome of certain bacterial and viral respiratory infections. However, these studies did ...
Enhanced immune response to pneumococcal infection in malnourished mice nasally treated with heat-killed Lactobacillus casei
(Wiley Blackwell Publishing, Inc, 2009-11)
The present study analyzed whether nasal administration of viable and non-viable Lactobacillus casei CRL 431 to immunocompromised mice was capable of increasing resistance against Streptococcus pneumoniae. Weaned micewere ...
Enhanced immune response to pneumococcal infection in malnourished mice nasally treated with heat killed Lactobacillus casei
(Wiley Blackwell Publishing, Inc, 2009-07)
The present study analyzed whether nasal administration of viable and non-viable Lactobacillus casei CRL 431 to immunocompromised mice was capable of increasing resistance against Streptococcus pneumoniae. Weaned mice were ...