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Identifying markers of tolerogenicity in dexamethasone-modulated monophosphoryl lipid A-activated dendritic cells.
(2016)
Background: Dendritic cells (DCs) are antigen presenting cells, able to initiate adaptive
immune responses or induce specific tolerance, depending on their maturation/activation
status. DCs with tolerance-promoting capacities ...
Identifying markers of tolerogenicity in dexamethasone-modulated monophosphoryl lipid A-activated dendritic cells.
(2016)
able
to
ini%ate
adap%ve
immune
responses
or
induce
specific
tolerance,
depending
on
their
matura%on/ac%va%on
status.
DCs
with
tolerance-‐promo%ng
capaci%es
(tolDCs)
represent
a
promising
immunotherapeu%c
tool
for
the
co ...
Identifying markers of tolerogenicity in dexamethasone-modulated monophosphoryl lipid a-activated dendritic cells.
(2016)
Background: Dendritic cells (DCs) are antigen presenting cells, able to initiate adaptive
immune responses or induce specific tolerance, depending on their maturation/activation
status. DCs with tolerance-promoting capacities ...
Differential transcriptional analysis in tolerogenic dendritic cells from rheumatoid arthritis patients and healthy subjects modulated with dexamethasone and monophosphoryl lipid A.
(2015)
Tolerogenic dendritic cells (tDCs) are promising therapeutics for rheumatoid arthritis (RA)
due to their capacity to modulate T cell-mediated immune responses. However, the
molecular basis underlying tDC differentiation ...
Transcriptional programs of monocyte-derived tolerogenic dendritic cells from rheumatoid arthritis patients and healthy subjects obtained by modulation with dexamethasone and monophosphoryl lipid A.
(2016)
Objective: Our
aim
was
to
study
the
gene
expression
paNern
of
monocyte-‐derived
tolerogenic
DCs
(tolDCs)
obtained
through
modulaUon
with
dexamethasone
and
monophosphoryl
lipid
A
(MPLA-‐tDCs)
in
order
to
idenUfy
molecul ...
Dexamethasone-conditioned monophosphoryl lipid A-activated dendritic cells derived from rheumatoid arthritis patients exhibit tolerogenic features and induce poor T cell responses to synovial antigens
(2014)
Objectives: Recently we have developed a shortened protocol for the generation of Tolerogenic dendritic cells (TolDCs) from monocytes of healthy volunteers using dexamethasone and monophosphoryl lipid A (MPLA). Here we ...