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Drug-resistance mechanisms and tuberculosis drugs
(Elsevier, 2015)
Bedaquiline and delamanid, novel classes of anti-tuberculosis drugs, have been recently approved for the treatment of multidrug-resistant tuberculosis. Antimicrobial resistance invariably follows the introduction of new ...
Combined antiparasitic treatment for neurocysticercosis - Authors' reply
(Elsevier, 2015)
We thank Aba Mahamat and colleagues for their comments on our Article1 and patient data illustrating a difficult case successfully treated with combined albendazole and praziquantel. We do not deem use of the combination ...
Second-line drug susceptibility breakpoints for Mycobacterium tuberculosis using the MODS assay
(International Union Against Tuberculosis and Lung Disease, 2014)
OBJECTIVE: To establish breakpoint concentrations for the fluoroquinolones (moxifloxacin [MFX] and ofloxacin [OFX]) and injectable second-line drugs (amikacin [AMK], kanamycin [KM] and capreomycin [CPM]) using the microscopic ...
A systematic review and meta-analysis of adjunctive therapies in diabetic foot ulcers
(Elsevier, 2016)
BACKGROUND: Multiple adjunctive therapies have been proposed to accelerate wound healing in patients with diabetes and foot ulcers. The aim of this systematic review is to summarize the best available evidence supporting ...
Estimation of the Antirelapse Efficacy of Tafenoquine, Using Plasmodium vivax Genotyping
(Oxford University Press, 2015)
UNLABELLED: Prevention of relapse of Plasmodium vivax infection is a key treatment goal in malaria. Use of P. vivax genotyping in a multicenter, double-blind, randomized, placebo-controlled phase 2b study in Peru, India, ...
Management of relapsing-remitting multiple sclerosis in Latin America: practical recommendations for treatment optimization
(Elsevier, 2014)
The Latin American MS Experts' Forum has developed practical recommendations on the initiation and optimization of disease-modifying therapies in patients with relapsing–remitting multiple sclerosis (RRMS). The recommendations ...
The influence of extra-therapeutic social support on the association between therapeutic bond and treatment outcome
(Routledge Journals, Taylor & Francis Ltd, 2020-10)
Objective: Both good therapeutic bond as well as extra-therapeutic social support seem to enhance treatment outcomes. Some features of the therapeutic bond are similar to experiences in extra-therapeutic relationships ...
Effects of dosage, comorbidities, and food on isoniazid pharmacokinetics in Peruvian tuberculosis patients
(American Society for Microbiology, 2014)
Poor response to tuberculosis (TB) therapy might be attributable to subtherapeutic levels in drug-compliant patients. Pharmacokinetic (PK) parameters can be affected by several factors, such as comorbidities or the interaction ...
Quality measurers of therapeutic communities for substance dependence: an international collaborative study survey in Latin America
(Springer, 2017)
BACKGROUND: In Latin America, substance related disorders are highly prevalent and one of the treatment strategies is the Therapeutic Communities (TCs), however, in Latin America there is scarce data about this treatment ...