Buscar
Mostrando ítems 1-10 de 253
Chaperones and their role in telomerase ribonucleoprotein biogenesis and telomere maintenance
(2019-01-01)
Telomere length maintenance is important for genome stability and cell division. In most eukaryotes, telomeres are maintained by the telomerase ribonucleoprotein (RNP) complex, minimally composed of the Telomerase Reverse ...
Leishmania amazonensis: Partial purification and study of the biochemical properties of the telomerase reverse transcriptase activity from promastigote-stage
(Academic Press Inc. Elsevier B.V., 2011-01-01)
Telomeres are protein-DNA complexes that protect chromosome ends from degradation and fusion. In Leishmania spp., telomeric DNA comprises a conserved TTAGGG repeat and is maintained by telomerase. Telomerase is a multisubunit ...
Leishmania amazonensis: Partial purification and study of the biochemical properties of the telomerase reverse transcriptase activity from promastigote-stage
(Academic Press Inc. Elsevier B.V., 2011-01-01)
Telomeres are protein-DNA complexes that protect chromosome ends from degradation and fusion. In Leishmania spp., telomeric DNA comprises a conserved TTAGGG repeat and is maintained by telomerase. Telomerase is a multisubunit ...
Telomerase regulation: a key to inhibition? (Review)
(Spandidos Publ Ltd, 2013-09)
Telomerase has been recognized as a common factor in most tumor cells, and in turn a distinctive feature with respect to non-malignant cells. This feature has made telomerase a promising target for cancer therapy. Telomerase ...
Leishmania amazonensis: Partial purification and study of the biochemical properties of the telomerase reverse transcriptase activity from promastigote-stage
(Academic Press Inc. Elsevier B.V., 2014)
Telomerase activity in peripheral blood mononuclear cells from HIV and HIV-HCV coinfected patients
(Elsevier Science, 2010-02)
Replicative senescence of peripheral blood mononuclear cells (PBMC) plays an important role in the pathophysiology of chronic viral infections. Although there are controversial reports concerning telomerase activity in HIV ...
The putative telomerase reverse transcriptase component of Leishmania amazonensis: gene cloning and characterization
(Springer, 2006-04-01)
The Leishmania amazonensis telomerase gene was cloned by a polymerase chain reaction-based strategy using primers designed from a Leishmania major sequence that shared similarities with conserved telomerase motifs. The ...
The putative telomerase reverse transcriptase component of Leishmania amazonensis: gene cloning and characterization
(Springer, 2006-04-01)
The Leishmania amazonensis telomerase gene was cloned by a polymerase chain reaction-based strategy using primers designed from a Leishmania major sequence that shared similarities with conserved telomerase motifs. The ...
A Trypanosoma brucei protein complex that binds G-overhangs and co-purifies with telomerase activity.
(Amer Soc Biochemistry Molecular Biology IncBethesdaEUA, 2002)