Collaborative efforts from the fields of biology, materials science, and engineering are leading to exciting progress in the development of nanomedicines. Since the targets of many therapeutic agents are localized in ...

Optimal pharmacotherapy occurs when we have selectivity and no toxicity. The discovery of specific pathways or enzymes that are vital forcell or parasite survival is also vital for the design of new specific, non-toxic ...

This paper presents an experimental assessment of photogrammetric targets and subpixel location techniques to be used with low contrast images such as images acquired by hyperspectral frame cameras. Eight different target ...

Targeted sanctions are increasingly used by the United Nations (UN) Security Council to address major challenges to international peace and security. Unlike other sanctions, those imposed by the UN are universally binding ...

MicroRNAs (miRNAs) are small noncoding RNAs that are recognized as posttranscriptional regulators of gene expression. These molecules have been shown to play important roles in several cellular processes. MiRNAs act on ...

We describe herein the therapeutic targets involved in Alzheimer’s disease as well as the available drugs and their synthetic routes. Bioactive compounds under development are also exploited to illustrate some recent ...

Drug discovery is a key process, given the rising and ubiquitous demand for medication to stay in good shape right through the course of one’s life. Drugs are small molecules that inhibit or activate the function of a ...