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The role of Pregnancy-Specific Glycoprotein 1a (PSG1a) in regulating the innate and adaptive immune response
(Wiley, 2013-02)
Among several explanations for the acceptance of the fetus, the one that suggests that the maternal immune system is suppressed or modified has been the subject of many studies. Thus, it has been proposed that the cells ...
TNF-alpha affects signature cytokines of th1 and th17 t cell subsets through differential actions on TNFR1 and TNFR2
(MDPI, 2022)
Tumor necrosis factor (TNF)- is a pleiotropic cytokine implicated in the etiology of
several autoimmune diseases, including rheumatoid arthritis (RA). TNF- regulates diverse effector
functions through the activation ...
Evidence for a modulatory effect of IL-10 on both Th1 and Th2 cytokine production: the role of the environment
(2011)
Allergic and other immune-mediated diseases are complex disease states determined by interplay between host genetics and environmental factors. Environmental changes such as fewer infections and reduced exposure to microbial ...
Elevation of NO Increases Ca2+ Entry and Resting Ca2+ and Na+ Concentrations in Skeletal Muscle Cells
(Cell Press, 2015)
Protein S-nitrosylation is a reversible post-translational modification and can
have profound effects on protein function in skeletal muscle. S-nitrosylation
has been proposed to exert regulatory effects on ion channels ...
Homens de negócio e poder local no oeste paulista
(Universidade Estadual Paulista (Unesp), 2018-04-10)
A presente tese tem como objetivo analisar o papel dos homens de negócio na constituição do poder local com base em uma perspectiva territorial e temporal comum: o Oeste Paulista, no período compreendido entre o final do ...
Intestinal host defense outcome is dictated by PGE(2) production during efferocytosis of infected cells
(Natl Acad Sciences, 2018-09-04)
Inflammatory responses are terminated by the clearance of dead cells, a process termed efferocytosis. A consequence of efferocytosis is the synthesis of the antiinflammatory mediators TGF-beta, PGE(2), and IL-10; however, ...
Upper crustal differentiation processes and their role in 238U-230Th disequilibria at the San Pedro-Linzor volcanic chain (Central Andes)
(PERGAMON-ELSEVIER SCIENCE LTD, 2020)