Now showing items 1-10 of 135
Cyclosporine improves remyelination in diabetic rats submitted to a gliotoxic demyelinating model in the brainstem
The use of cyclosporine (CsA) has shown to induce an increase in density of oligodendrocytes near remyelinating areas following the injection of ethidium bromide (EB), a demyelinating agent, in the rat brainstem. It is ...
Propentofylline reverses delayed remyelination in streptozotocin-induced diabetic rats
(Sbem-soc Brasil Endocrinologia & Metabologia, 2015-02-01)
Objective: The diabetic state induced by streptozotocin injection is known to impair oligodendroglial remyelination in the rat brainstem following intracisternal injection with the gliotoxic agent ethidium bromide (EB). ...
The role of galectin-3: From oligodendroglial differentiation and myelination to demyelination and remyelination processes in a cuprizone-induced demyelination model
(Springer International Publishing, 2016-10)
The aim of this work was to combine our previously published results with our new data to show how galectin-3 (Gal-3) controls myelin integrity and function, promotes oligodendroglial cell differentiation, and regulates ...
Dynamics of remyelination in the brain of adult rats after exposure to ethidium bromide
(Editrice Compositori BolognaBolognaItália, 1998)
Thyroid hormones promote differentiation of oligodendrocyte progenitor cells and improve remyelination after cuprizone-induced demyelination
(Academic Press Inc Elsevier Science, 2008-08)
In the present work we analyzed the capacity of thyroid hormones (THs) to improve remyelination using a rat model of cuprizone-induced demyelination previously described in our laboratories. Twenty one day old Wistar rats ...
Biology of the repair of central nervous system demyelinated lesions
(Assoc Arquivos De Neuro- PsiquiatriaSao Paulo SpBrasil, 1996)
Demyelination-remyelination in the CNS: ligand-dependent participation of the Notch signaling pathway
(Oxford University Press, 2019-06)
Multiple sclerosis (MS) is an immune-mediated central nervous system disease mostly affecting young people. Multiple sclerosis and other neurodegenerative and white matter disorders involve oligodendrocyte (OL) damage and ...
Demyelination and remyelination after multiple intramedullary injections of ethidium bromide in Wistar rats
(Assoc Arquivos De Neuro- PsiquiatriaSao Paulo SpBrasil, 1997)
The Notch Signaling Pathway: Its Role in Focal CNS Demyelination and Apotransferrin-Induced Remyelination
Oligodendroglial damage and demyelination are common pathological features characterizing white matter and neurodegenerative disorders. Identifying the signaling pathways involved in myelin repair through oligodendroglial ...