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Recurrences of multidrug‐resistant tuberculosis: Strains involved, within‐host diversity, and fine‐tuned allocation of reinfections
(Wiley Blackwell Publishing, Inc, 2022-03)
Recurrent tuberculosis occurs due to exogenous reinfection or reactivation/persistence. We analysed 90 sequential MDR Mtb isolates obtained in Argentina from 27 patients with previously diagnosed MDR-TB that recurred in ...
Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment
(BioMed Central, 2021-04-29)
Background: Whole-genome sequencing has shown that the Mycobacterium tuberculosis infection process can be more heterogeneous than previously thought. Compartmentalized infections, exogenous reinfections, and microevolution ...
Patterns and processes of mycobacterium bovis evolution revealed by phylogenomic analyses
(Oxford University Press, 2017-03)
Mycobacterium bovis is an important animal pathogen worldwide that parasitizes wild and domesticated vertebrate livestock as well as humans. A comparison of the five M. bovis complete genomes from the United Kingdom, South ...