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Cross-talk between mitochondrial function, growth, and stress signalling pathways in plants
(Oxford University Press, 2020-12)
Plant mitochondria harbour complex metabolic routes that are interconnected with those of other cell compartments and changes in mitochondrial function remotely influence processes in different parts of the cell. This ...
Persistent activation of the mammalian target of rapamycin signaling pathway in cutaneous squamous cell carcinomas in cats
(Wiley Blackwell Publishing, Inc, 2021-07)
Background: Cutaneous squamous cell carcinoma (CSCC) represents the most common malignant tumour of the feline skin. Emerging evidence suggests that the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin ...
Mechanotransduction pathways in skeletal muscle hypertrophy
(INFORMA HEALTHCARELONDON, 2012)
In the last decade, molecular biology has contributed to define some of the cellular events that trigger skeletal muscle hypertrophy. Recent evidence shows that insulin like growth factor 1/phosphatidyl inositol 3-kinase/protein ...
Leptin induces macrophage lipid body formation by a phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent mechanism
(American Society for Biochemistry and Molecular Biology, 2019)
Protein Blend and Casein Supplementations before Inactive Phase Similarly Activate Mechanistic Target of Rapamycin Signaling in Rat Skeletal Muscle
(Wolters Kluwer Medknow Publications, 2020-07-01)
During overnight sleep, the longest postabsorptive and inactive phase of the day causes protein catabolism and loss. However, the daytime ingestion of dairy proteins has been shown to stimulate muscle protein synthesis and ...
Placental STAT3 signaling is activated in women with polycystic ovary syndrome
(Oxford University Press, 2015)
© 2015 The Author. study question: Does polycystic ovary syndrome (PCOS) in women without pregnancy complications affect placental signal transducer and activator of transcription 3 (STAT3) and mechanistic target of rapamycin ...
Mammalian Target of Rapamycin Inhibition in Trypanosoma cruzi-Infected Macrophages Leads to an Intracellular Profile That Is Detrimental for Infection
(Frontiers Media S.A., 2018-02)
The causative agent of Chagas' disease, Trypanosoma cruzi, affects approximately 10 million people living mainly in Latin America, with macrophages being one of the first cellular actors confronting the invasion during T. ...
Signal transduction pathways in FSH regulation of rat sertoli cell proliferation
(American Physiological Society, 2012-04)
The final number of Sertoli cells reached during the proliferative periods determines sperm production capacity in adulthood. It is well known that FSH is the major Sertoli cell mitogen; however, little is known about the ...