Now showing items 1-10 of 22
Cell Therapy with Bone Marrow Mononuclear Cells in Elastase-Induced Pulmonary Emphysema
Emphysema is characterized by destruction of alveolar walls with loss of gas exchange surface and consequent progressive dyspnea. This study aimed to evaluate the efficiency of cell therapy with bone marrow mononuclear ...
Unicentric study of cell therapy in chronic obstructive pulmonary disease/pulmonary emphysema
(Dove Medical Press Ltd, 2011-01-01)
Within the chronic obstructive pulmonary disease (COPD) spectrum, lung emphysema presents, as a primarily histopathologic feature, the destruction of pulmonary parenchyma and, accordingly, an increase in the airflow ...
Alterations in pulmonary structure by elastase administration in a model of emphysema in mice is associated with functional disturbances
(Elsevier Doyma Sl, 2012-05-01)
Several experimental studies of pulmonary emphysema using animal models have been described in the literature. However, only a few of these studies have focused on the assessment of ergometric function as a non-invasive ...
Recovery of pulmonary structure and exercise capacity by treatment with granulocyte-colony stimulating factor (G-CSF) in a mouse model of emphysema
Emphysema is a chronic obstructive pulmonary disease characterized abnormal dilatation of alveolar spaces, which impairs alveolar gas exchange, compromising the physical capacity of a patient due to airflow limitations. ...
Animal models in chronic obstructive pulmonary disease-an overview
(Informa Healthcare, 2015)
Phase I clinical trial of cell therapy in patients with advanced chronic obstructive pulmonary disease: follow-up of up to 3 years
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2014)
A Plant Proteinase Inhibitor from Enterolobium contortisiliquum Attenuates Pulmonary Mechanics, Inflammation and Remodeling Induced by Elastase in Mice
(Mdpi Ag, 2017)
Proteinase inhibitors have been associated with anti-inflammatory and antioxidant activities and may represent a potential therapeutic treatment for emphysema. Our aim was to evaluate the effects of a plant Kunitz proteinase ...
The plant-derived bauhinia bauhinioides kallikrein proteinase inhibitor (rbbki) attenuates elastase-induced emphysema in mice
(Acta Cirurgica Brasileira, 2016)
Background. Elastase mediates important oxidative actions during the development of chronic obstructive pulmonary disease (COPD). However, few resources for the inhibition of elastase have been investigated. Our study ...
Enfisema lobar congênito: série de casos de 30 anos em dois hospitais universitários
Objetivo: Revisar os casos de enfisema lobar congênito (ELC) operados nos últimos 30 anos em dois hospitais universitários. Métodos: Foram revistos os prontuários médicos das crianças com ELC operadas no Hospital das ...