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Bacterial nitrate reductases: Molecular and biological aspects of nitrate reduction
(Elsevier Science Inc, 2006-05)
Nitrogen is a vital component in living organisms as it participates in the making of essential biomolecules such as proteins, nucleic acids, etc. In the biosphere, nitrogen cycles between the oxidation states +V and -III ...
Tyr-nitration in maize CDKA;1 results in lower affinity for ATP binding
(Elsevier Science, 2020-10)
Cyclin-dependent kinase A (CDKA) is a key component for cell cycle progression. The catalytic kinase activity depends on the protein's ability to form an active complex with cyclins and on phosphoregulatory mechanisms. ...
Conjugated linoleic acid is a preferential substrate for fatty acid nitration
(American Society for Biochemistry and Molecular Biology, 2012-12)
The oxidation and nitration of unsaturated fatty acids by oxides of nitrogen yield electrophilic derivatives that can modulate protein function via post-translational protein modifications. The biological mechanisms ...
The alkaline transition of cytochrome c revisited: Effects of electrostatic interactions and tyrosine nitration on the reaction dynamics
(Elsevier Science Inc, 2019-04)
Here we investigated the effect of electrostatic interactions and of protein tyrosine nitration of mammalian cytochrome c on the dynamics of the so-called alkaline transition, a pH- and redox-triggered conformational change ...
Early events following phosphorus restriction involve changes in proteome and affects nitric oxide metabolism in soybean leaves
(Pergamon-Elsevier Science Ltd, 2019-05)
Phosphorus (P) is a macronutrient with structural and regulatory functions, essential for energy transfer. Under limited P availability, plant cells respond to internal signals, adjusting their metabolic pathways in order ...
Exploring the molecular basis of human manganese superoxide dismutase inactivation mediated by tyrosine 34 nitration
(Elsevier Science Inc, 2011-03)
Manganese Superoxide Dismutase (MnSOD) is an essential mitochondrial antioxidant enzyme that protects organisms against oxidative damage, dismutating superoxide radical (O2-) into H2O2 and O2. The active site of the protein ...
Tyrosine oxidation and nitration in transmembrane peptides is connected to lipid peroxidation
(Elsevier Science Inc, 2017-05)
Tyrosine nitration is an oxidative post-translational modification that can occur in proteins associated to hydrophobic bio-structures such as membranes and lipoproteins. In this work, we have studied tyrosine nitration ...
Dietary nitrate metabolism and enteric methane mitigation in sheep consuming a protein-deficient diet
(CSIRO Publishing, 2019-09-20)
It was hypothesised that the inclusion of nitrate(NO3 –) or cysteamine hydrochloride (CSH) in a protein deficient diet (4.8% crude protein; CP) would improve the productivity of sheep while reducing enteric methane (CH4) ...
EPR and redox properties of periplasmic nitrate reductase from Desulfovibrio desulfuricans ATCC 27774
(Springer, 2006-07)
Nitrate reductases are enzymes that catalyze the conversion of nitrate to nitrite. We report here electron paramagnetic resonance (EPR) studies in the periplasmic nitrate reductase isolated from the sulfate-reducing bacteria ...